1. Tofu contains a lot of purine. Gout patients with abnormal purine metabolism and patients with increased blood uric acid concentration should eat tofu with caution.

2. Tofu is cold in nature, and those who usually have a cold stomach should not eat it if they experience chest tightness, nausea, etc. after eating tofu.

3. People who are prone to diarrhea, abdominal distension and spleen deficiency should not eat more tofu.

4. It is not advisable to eat tofu when taking tetracycline drugs, because foods made with tofu contain more calcium, and gypsum made with salt brine contains more magnesium. When tetracycline encounters calcium, , magnesium will react and reduce the bactericidal effect.