The uncoupling agent can form a proton channel on the mitochondria, allowing protons to return to the mitochondrial matrix without passing through F0F1-ATP synthase, thereby rapidly consuming the transmembrane proton gradient and converting the stored proton gradient into Electrochemical energy is converted into heat energy, which hinders the synthesis of ATP, thereby increasing the biological oxidation of fat and other substances, which can achieve the effect of weight loss. However, it is not used at present because it can easily cause the person taking the medicine to have high body temperature, convulsions, coma, etc. phenomenon, even leading to death.