DTP vaccine flows to Changchun Changsheng Company for rabies vaccine production violations, and many disease control departments have responded one after another.
Since July 16, many disease control departments have responded. As of July 22nd, at least 20 disease control departments of provinces, autonomous regions and municipalities directly under the Central Government have voiced their voices about the Changchun longevity vaccine incident.
Centers for Disease Control and Prevention including Shanghai, Henan, Hainan, Chongqing, Shandong, Shanxi, Guangxi, Hebei and other provinces and cities have clearly stated that Changchun Changsheng rabies vaccine will be completely stopped or suspended.
Hunan, Fujian, Guangdong and other provincial centers for disease control and prevention said that there were no batches of rabies vaccine involved in this province.
In addition, the disease control departments of Tibet, Beijing, Tianjin, Jiangxi and other provinces said that they had not purchased rabies vaccine products from Changchun Changsheng Company, nor had they purchased vaccine batches involved.
Where did the unqualified DTP vaccine go? Hebei: Unqualified DTP vaccine flows to Shijiazhuang, Langfang and Dingzhou.
On July 23rd, the Center for Disease Control and Prevention of Hebei Province released a message in official website, saying that, in view of the fact that the unqualified adsorbed acellular DTP vaccine produced by Wuhan Institute of Biological Products Co., Ltd. was sold to Hebei Province, after careful verification, it flowed to Shijiazhuang, Langfang and Dingzhou, and * *143941person used the unqualified vaccine. The unqualified titer of DTP vaccine may affect the immune protection effect, but it has no effect on human safety. After monitoring by the monitoring system of abnormal reaction of vaccination, no abnormal fluctuation of suspected abnormal reaction of vaccination was found.
In order to ensure the health of children who have been vaccinated with unqualified DTP vaccine, Hebei Province uses qualified DTP vaccine and carries out routine vaccination with subsequent doses of DTP vaccine according to the immunization procedures stipulated by the state. At the same time, according to the deployment of the national, provincial health and family planning commission and food and drug administration, the provincial CDC has communicated and coordinated with vaccine companies many times, forming an implementation plan for replanting. The enterprise will provide DTP vaccine for replanting and syringes for inoculation to Hebei Province in the near future. After vaccines and syringes are in place, replanting will be carried out quickly.
In addition, on July 2 1 day, according to the official WeChat @ Hebei Comprehensive Broadcasting of Hebei Radio and Television Station, Zhang Zhenguo, director of the immunization planning management office of Hebei Provincial Center for Disease Control and Prevention, introduced that the rabies vaccine produced by Changchun Changsheng was in the procurement catalogue of Hebei Province. At present, disease control institutions across the province have completely stopped using and sealed the rabies vaccine produced by this enterprise.
Shandong: The unqualified DTP vaccine flows to 8 cities, and 247,359 vaccines have been vaccinated.
According to the news quoted by Shandong CDC in Popular Daily, Changchun Changsheng Company sold 252,600 unqualified DTP vaccines in Shandong Province, accounting for 3.96% of the province's annual consumption. They went to eight cities including Jinan, Zibo, Yantai, Jining, Tai 'an, Weihai, Rizhao and Laiwu. This batch of vaccines has inoculated 247,359, and 524 1 vaccine was lost and sealed, involving 2 1 vaccine, 5/kloc-0 vaccine, and 84 children. Children's vaccination information has been registered in the vaccination unit in detail. No abnormal reaction of suspected vaccination was found among the children involved.
On July 18, the official WeChat of Shandong Provincial Center for Disease Control and Prevention @ Shandong Provincial Center for Disease Control and Prevention announced that Shandong Province had completely stopped using the human rabies vaccine produced by Changchun Changsheng Biotechnology Co., Ltd., and further information needs to wait for the follow-up notice from National Medical Products Administration and vaccine manufacturers.
Guangdong: No batches of vaccines have been purchased.
Experts from the Guangdong Provincial Center for Disease Control and Prevention responded on the 22 nd that at present, the province has not purchased the batch of DTP vaccine notified by the State FDA earlier; The previously notified rabies vaccine has not yet left the factory, so there is no batch of rabies vaccine involved by the company in Guangdong Province.
Beijing: Changchun Changsheng two vaccines have not been purchased.
The Beijing Municipal Center for Disease Control and Prevention said that there was no tender for these two vaccines in Beijing.
Zhejiang: No problem vaccine inflow was found.
On the evening of July 22, the US Food and Drug Administration in Zhejiang Province said that after the investigation of vaccine storage and distribution enterprises in Zhejiang Province, no problem rabies vaccine and DTP vaccine with batch number 201605014-01were found.
Shanghai: Changchun Changsheng rabies vaccine has been completely stopped.
On July 16, the official WeChat account of Shanghai Center for Disease Control and Prevention announced that Changchun Changsheng rabies vaccine had been completely discontinued in Shanghai. Further information needs to wait for the follow-up notice from National Medical Products Administration and vaccine manufacturers.
Shanghai CDC said that if you have been vaccinated with Changchun Changsheng rabies vaccine for a period of time, you can choose other brands of rabies vaccine that also adopt the "five-needle method".
Henan: Suspension of use and local storage of all rabies vaccines in Changchun Changsheng.
July 17, according to Dahe Daily. Com, Henan Darun Biopharmaceutical Co., Ltd., which is responsible for the promotion, storage and transportation of Changchun Changsheng vaccine in Henan, informed that the company had notified the county-level CDC in Henan at 5 pm on July 15, requesting it to suspend the use and seal all Changchun Changsheng rabies vaccines on the spot.
According to the above report, as of noon on July 17 12, the number of Changchun longevity rabies vaccines reported and sealed in Henan Province is 14 1380.8 (5 per person), which is expected to account for more than 90% of the total market of Changchun longevity rabies vaccines in Henan.
On July 18, the official WeChat @ of Henan CDC released a message saying that there was no vaccine involved in Henan. In the question-and-answer article published by @ Henan CDC, Henan CDC said that the announcement of the State Administration of Medical Products pointed out that all the batches of products involved in this flight inspection have not been shipped and marketed, and all products have been effectively controlled.
Hainan: Changchun Changsheng rabies vaccine has been completely stopped.
On July 23, Hainan CDC said that Hainan had completely stopped using the freeze-dried rabies vaccine for human use produced by Changchun Changsheng Biotechnology Co., Ltd., and other manufacturers had sufficient supply of freeze-dried rabies vaccine to ensure the normal prevention and disposal of rabies exposure in Hainan.
Hainan Provincial Center for Disease Control and Prevention reminded that if the enterprise has been vaccinated with freeze-dried rabies vaccine and has not completed the whole vaccination, it can use another brand of freeze-dried rabies vaccine and continue to complete the whole vaccination according to the original procedure; Those who have completed the whole vaccination are waiting for further notice from the State Administration of Pharmaceutical Products, and it is not recommended to vaccinate again at present.
Chongqing: Suspension of use and local storage of Changchun Changsheng rabies vaccine
On July 18, Chongqing CDC released a message on WeChat WeChat official account @ Chongqing CDC, saying that since July 15, the use of freeze-dried rabies vaccine for human use by Changchun Changsheng Biotechnology Co., Ltd. was suspended and sealed on the spot.
Shanxi: Changchun Changsheng rabies vaccine has been discontinued.
On July 19, official website, Shanxi Provincial Center for Disease Control and Prevention, announced that Changchun Changsheng Rabies Vaccine had been stopped at all inoculation sites in the province according to the notice of the State Administration of Medical Products and the urgent notice of Changchun Changsheng Biotechnology Co., Ltd.
According to the opinion of National Health Commission CDC, people who have been vaccinated with Changchun Changsheng rabies vaccine at all inoculation points in the province are choosing rabies vaccines from other manufacturers and continuing to be vaccinated according to the original vaccination procedures.
Guangxi: 58 counties (cities, districts) have recalled 93,384 pieces.
On July 19, Guangxi CDC WeChat WeChat official account @ Guangxi CDC announced that there was no vaccine involved in Guangxi.
Guangxi CDC mentioned that there are 1 1 companies that have entered the second-class vaccine procurement system of Guangxi Public Resource Trading Center. By July 2065, the procurement system had distributed 438+08,65,438,500,000 rabies vaccines. This enterprise (refers to Changchun Changsheng).
Guangxi CDC said that Changchun Changsheng Company took the initiative to recall, which was a company behavior. As of July 20 18, 93,384 pieces were recalled in 58 counties (cities, districts) in Guangxi.
According to local media reports on July 20th, the freeze-dried rabies vaccine for human use produced by Changchun Changsheng Biotechnology Co., Ltd. has been completely discontinued in Guangxi. The disease control department of the autonomous region will pay close attention to the progress of this incident and announce the relevant handling situation in time.
Fujian: No rabies vaccine batch was involved, and unqualified DTP vaccine was not purchased.
On July 23, the official WeChat account of Fujian CDC @ Fujian CDC released a message saying that Fujian Province had not purchased the DTP vaccine with unqualified titer notified by the US Food and Drug Administration earlier, and the vaccine involved had no impact on the whole province.
19 In July, the Fujian Provincial Center for Disease Control and Prevention said that according to the Catalogue of Procurement of Class II Vaccines in Fujian Province in 20 18, rabies vaccines from Changchun Changsheng and other 10 manufacturers entered the provincial procurement catalogue, and some counties and districts purchased them. However, because all the batches of products involved in flight inspection have not yet left the factory and gone on sale, all products have been effectively controlled.
Qinghai has not yet responded to whether there is a related problem of vaccine inflow.
On July 19, Qinghai Provincial Center for Disease Control and Prevention reported on WeChat WeChat official account @ Qinghai CDC. It is understood that the State Administration of Pharmaceutical Products is organizing an investigation of enterprises. According to the Code for Prevention and Disposal of Rabies Exposure, if the whole vaccination procedure has not been completed, you can choose rabies vaccines from other manufacturers and continue to vaccinate according to the original vaccination procedure.
Hunan: Hunan does not involve vaccines.
On July 20th, the official account of WeChat of Hunan CDC @ Hunan CDC reported that according to the announcement of the State Administration of Medical Supplies and the enterprises involved, all the products involved in this inspection have not left the factory and gone on sale, and all the products have been effectively controlled. On July 16, Changchun Changsheng, the company involved, announced that in order to ensure the safety of medication, Changchun Changsheng was recalling all freeze-dried rabies vaccines for human use within the validity period of batches. Hunan CDC said that Hunan does not involve vaccines.
Jiangsu: Vaccines are purchased by unified bidding through batch issuance, inspection and audit.
On July 20th, according to the official WeChat of Jiangsu CDC @ Jiangsu CDC, at present, all the vaccines in Jiangsu Province have passed the batch inspection and review, and then they can be distributed to all inoculation points through unified bidding and procurement through formal channels for everyone to inject.
Jiangsu CDC introduced that since 2006, China has implemented a batch issuance system for all listed vaccines, that is, each batch of vaccines must be subject to compulsory inspection and audit when they leave the factory or are imported. Under this system, every batch of biological products produced by an enterprise must go through sampling, inspection, data review and inspection before it can be listed. Those who fail to pass the inspection or the audit do not meet the requirements shall not be listed or imported.
According to the report of Yangzhou Evening News in July 19, the rabies vaccine of Liaoning Chengda is currently used in most areas of Yangzhou. Measures have been taken to deal with a few areas where Changchun Changsheng Company's vaccine is used: First, actively cooperate with Changchun Changsheng Company to seal up its rabies vaccine; The second is to stop purchasing and using its rabies vaccine; Three, according to the "guidelines for rabies vaccination" and "guidelines for second-class vaccines in Jiangsu Province", the recipients who have been vaccinated with Changchun Changsheng vaccine and have not completed the whole vaccination.
Tibet: No vaccine with problems was purchased.
On July 22nd, according to the official WeChat of Tibet CDC @ Tibet CDC, Xizang Autonomous Region CDC attached great importance to the vaccine incident, and arranged special personnel to investigate the procurement, supply and inventory of the corresponding vaccines again. Thirdly, Xizang Autonomous Region has never purchased "rabies vaccine for human use" and "adsorption cell-free DTP combined vaccine" from Changchun Changsheng, and has no business contact with this company.
The Center for Disease Control and Prevention in Tibet indicated that it had not purchased or used the cell-free DTP vaccine with batch number 20 1607050-2 produced by Wuhan Institute of Biology (according to the information released by the State Medical and Drug Administration, these two batches of problematic vaccines were sold to Shandong, Chongqing and Hebei respectively). Please rest assured that the majority of Tibetan citizens are vaccinated.
Shaanxi: The unqualified batch of DTP was not purchased.
On July 22nd, according to the report of China Business Daily, it was learned from the Shaanxi Provincial Center for Disease Control and Prevention that there was no batch of DTP vaccine involved in the bidding procurement in Shaanxi Province. Please rest assured. In addition, the freeze-dried rabies vaccine for human use detected by the State Medical and Drug Administration has not yet left the factory, and all other batches of rabies vaccines produced by the company have also been recalled.
Tianjin: Changchun Changsheng rabies vaccine was not purchased.
On July 22, according to Jinyun News, the relevant person in charge of Tianjin Center for Disease Control and Prevention said in an interview that the city did not purchase rabies vaccine produced by Changchun Changsheng.
Tianjin CDC said that the manufacturers purchasing rabies vaccine in Tianjin are: Jilin Maifeng Biopharmaceutical Co., Ltd., Liaoning Chengda Biopharmaceutical Co., Ltd., Chengdu Kang Hua Biological Products Co., Ltd., Guangzhou Cheng Nuo Biological Products Co., Ltd., Ningbo Rongan Biopharmaceutical Co., Ltd. and GlaxoSmithKline Co., Ltd. ..
Sichuan: The problem of freeze-dried rabies vaccine for human use has all been recalled and has not entered the society.
On July 22, according to Sichuan Online, the problem of freeze-dried rabies vaccine for human use has all been recalled and has not entered the society. The public can rest assured that the problem "DTP" vaccine did not involve relevant batches of vaccines in the bidding and procurement of vaccines in Sichuan Province.
Jiangxi: No batches of vaccines have been purchased.
On July 22, the Jiangxi Provincial Center for Disease Control and Prevention released a message through the official WeChat, and Jiangxi Province did not purchase the batches of vaccines involved.
Anhui: The rabies vaccine of Changchun Changsheng Company was completely stopped, and the problem DTP vaccine did not flow in.
On July 23, the website of Anhui Provincial Health Planning Commission released the answers to recent vaccine-related questions from Anhui Provincial Center for Disease Control and Prevention. According to the article, at present, Anhui Province has stopped selling all rabies vaccines of Changchun Changsheng Company. For those who have been injected with part of Changchun Changsheng rabies vaccine but have not completed the whole vaccination, they can use another brand of rabies vaccine to complete the follow-up vaccination according to the information publicly released by the State Medical and Drug Administration and the CDC of the National Health and Wellness Commission and the requirements of the National Code for Prevention and Disposal of Rabies Exposure.
In addition, the titer index of DTP vaccine with batch number 201605014-01produced by Changchun Changsheng Biotechnology Co., Ltd. and batch number 20 1607050-2 produced by Wuhan Institute of Biological Products Co., Ltd. did not meet the standard. Anhui province did not purchase the above batch of DTP vaccine, and the above batch of DTP vaccine did not flow into the province.