The cleanroom in pharmaceutical industry is different from other industrial cleanrooms, especially in aseptic production. It is necessary to control not only the aerosol particles suspended in the air, but also the number of living microorganisms, that is, to provide a so-called "aseptic" environment (aseptic room). Of course, "sterility" is relative and can be expressed by sterility assurance rate STA. So what are the disinfection methods of GMP clean room?

Methods of obtaining sterile air in pharmaceutical industry can be roughly divided into two categories:

1, sterilization

Protein denaturation of bacteria in air can be achieved by heating (dry heat, wet heat), chemical reagents (such as formaldehyde and cyclohexane oxide), ozone and radiation (such as ultraviolet lamp irradiation).

Step 2 disinfect

Use filter media (such as various air filters and high efficiency filters) or electrostatic dust removal methods to capture and intercept dust and miscellaneous bacteria in the air.

In fact, industrial sterilization methods are often not single, but a combination of the two. For flowing air (such as HVAC system and compressed air), filter media is commonly used to sterilize, and for air in static environment, sterilization method is commonly used to sterilize aseptic room, culture room, transmission window and clothes.