1. Vehicle rental fee: It is estimated to be around ** 1000 yuan * * depending on the vehicle model and the rental duration.

2. Fuel cost: According to the driving distance and vehicle fuel consumption, it is estimated that it will cost about ** 1000 yuan * *.

3. Accommodation cost: it is estimated to be about ** 1000 yuan * * depending on the hotel selected and the length of stay.

4. Catering expenses: according to different personal tastes and eating habits, it is estimated to be around ** 1000 yuan * *.

5. Ticket fee: According to the different scenic spots visited, it is estimated to be around **500 yuan.

Based on the above expenses, the total cost of self-driving from Bozhou to the Sichuan-Tibet line in southern Anhui for 3 days and 2 nights is about * * 4,500 yuan * *. Please note that this fee is for reference only, and the actual fee may vary according to personal needs, itinerary, hotel and air ticket price.