Gastric ulcer is a common disease in China. Whether it will become cancerous has always been a concern of patients and doctors. In recent years, some new discoveries have been made in the research of evidence-based medicine, which deserves the vigilance of middle-aged and elderly patients with gastric ulcer. Can gastric ulcer become cancerous? Let's take a look at the reasons!
Knowledge of canceration of gastric ulcer
What is the probability of canceration
The results of long-term follow-up of patients with gastric ulcer by experts at home and abroad in the 1961s and 1981s show that the canceration rate of gastric ulcer is 5%~11%, and some reports think it is higher. However, due to the examination and diagnosis methods at that time, the data were not accurate. Since the application of air-barium double contrast radiography and fiber gastroscope in China, there are technical conditions to further study and count the canceration rate of gastric ulcer. A special group on gastric ulcer canceration was established in China. After investigation and statistics of 3 441 cases of benign and malignant gastric ulcer all over the country, the result showed that the canceration rate was 1.96%. It should be said that this figure is more objective.
There are many patients with gastric ulcer in China, and even the canceration rate of 1.96% is not small. Strictly speaking, the mechanism of gastric ulcer canceration is not the canceration of ulcer itself, but the canceration of mucosa around ulcer due to repeated stimulation of inflammation. It is of great significance to reduce the occurrence and recurrence of gastric ulcer and cure it in time.
Early signs of canceration
1. The patient is over 35 years old and has a history of ulcer for many years. The typical symptoms of ulcer suddenly changed obviously under unknown factors, and the drugs with good therapeutic effect suddenly showed poor therapeutic effect, especially the abnormal phenomenon that antacid drugs were ineffective.
2. The regular pain of gastric ulcer disappears dramatically and is replaced by persistent irregular abdominal pain.
3. The patient is tired, tired, weak, anorexia, and has indigestion diarrhea, especially after eating meat food.
3. The patient's general condition changed sharply in a short period of time, with poor nutritional status, obvious emaciation, rapid weight loss, anemia and intractable vomiting without effective treatment.
4. The patient has a low fever of unknown cause, with the general body temperature below 38 degrees Celsius, occult bleeding in stool, and the fecal occult blood test is positive, which often lasts for one to two months, and gastric juice test can not find gastric acid.
5. The patient's signs changed, and the upper abdomen was full and swollen, and the mass could be palpated. If there is left supraclavicular lymph node enlargement, it means that the cancer has entered the advanced stage.
If the above-mentioned symptoms of ulcer deterioration and some abnormal signs that have never been seen before are found, X-ray barium meal, special ultrasound and other examinations should be done in time, and gastroscopy or biopsy pathological diagnosis should be done if possible, so as to achieve early diagnosis and early treatment and achieve the ideal treatment purpose.
How to prevent cancer
1. Check regularly after recovery: Patients with gastric ulcer should adhere to systematic and regular treatment, and continue to take medicine for half a year to 1 years after recovery, and the dosage can be halved or according to the doctor's advice, in order to prevent recurrence. After systematic treatment, patients with gastric ulcer under 35 years old who are confirmed to be cured by gastroscopy are less likely to develop cancer, and those who have the conditions can be reexamined 1 years after being cured. Patients over 35 years old with gastric ulcer should be reexamined 1 times in 1~2 years after being cured, and it is best to reexamine gastroscope in order to find small cancer focus in time.
For patients with obvious intestinal metaplasia or dysplasia around gastric ulcer, after the ulcer is cured, it must be reexamined 1 times a year, and mucosal biopsy should be done. It is best for these patients to establish a follow-up relationship with the hospital.
2. timely examination and treatment: recurrent gastric ulcer, or ulcer with a diameter of more than 2 cm, or peripheral inflammation, erosion, hyperplasia and uneven basement should be considered for surgical resection on the basis of strict review and biopsy. Gastric ulcer diagnosed by X-ray must be followed up. If it is not cured in time, it is best to do gastroscopy to rule out early gastric cancer. Some patients with ulcer gastric cancer can temporarily relieve their symptoms after taking painkillers and cimetidine, so it is best not to rely on feelings, but to take them seriously and check them in time.
In addition, patients with gastric ulcer should pay attention to eating on time, do not overeat, eat less spicy, salted and smoked food, eat more vegetables and fruits, and eat more garlic. Keep a happy mood and don't sulk.