Yes, the epidemic has had a great impact on many enterprises and shops, leading to the closure of many shops. This is mainly due to the following reasons:

1. Measures: In order to control the spread of the epidemic, the government has taken a series of measures, such as closing the city, restricting the flow of people, and suspending business and classes. These measures have directly led to the failure of many offline physical stores to operate normally, unable to obtain income, and difficult to maintain operations, leading to the closure of many stores.

2. Brain drain: Due to the impact of the epidemic, many people have to leave their jobs and cannot work in the store, resulting in the store's failure to operate normally. At the same time, some employees are sick and leave their posts because of the epidemic, which also directly affects the operation of the store.

3. supply chain interruption: due to the influence of epidemic control, the transportation of raw materials and goods has suffered great difficulties, resulting in many shops unable to obtain the required raw materials and equipment, and it is difficult to maintain normal production and operation.

4. consumption shrinkage: affected by the epidemic, people's willingness and ability to consume declined, resulting in consumption shrinkage and sales decline. This is a fatal blow to many shops and cannot support their operation and survival.

The epidemic situation has different impacts on enterprises and shops in different industries, regions and sizes, but overall, the epidemic situation is one of the factors that cause many shops to close down.