Aidisha (mesalazine sustained-release granules) has a good effect on the treatment of inflammatory bowel disease. So can Aidisha (Mesalazine Sustained-release Granule) treat colitis together with traditional Chinese medicine? Before 1980s, the incidence of UC in Europe was relatively high. However, with the rapid development of China's economy, changes in diet structure, increasing employment pressure, environmental pollution and genetic factors, the incidence of UC is increasing year by year, and it has become a common clinical disease. In recent years, most scholars believe that the pathogenesis of UC is closely related to abnormal immune function and increased production of inflammatory transmitters. If we can block or inhibit the immune response and the role of specific receptors; Reduce or inhibit prostaglandin-like substances, leukotrienes, platelet activating factors, some cytokines, oxygen free radicals, neuropeptides, substance P, vasoactive peptides, etc. , can effectively alleviate the condition. The traditional treatment is oral administration of 5-ASA, but some patients may have obvious gastrointestinal reaction, leukopenia and liver function damage after taking 5-ASA. Therefore, on the basis of taking Aidisha, self-made prescriptions (Sanguisorba officinalis 50 g, Bletilla striata 50 g, Acorus gramineus 50 g) were added. The results showed that the total effective rate of the treatment group was the total effective rate of Aidisha (Mesalazine Sustained-release Granules) alone, indicating that the combination of traditional Chinese medicine can improve the histopathology of the lesions during the treatment period. There was significant difference in clinical efficacy between the two groups (P