The product has anti-inflammatory, antipyretic and analgesic effects, and is a PG synthase inhibitor. Oral absorption is rapid and complete, and the plasma concentration reaches the peak 2-4 hours after each dose of/kloc-0. More than 99% of the blood binds to plasma protein, and the t 1/2 is 13 ~ 14 hours. About 95% is excreted in urine in the form of prototype and metabolite. It has positive effects on rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, chronic degenerative diseases of motor system (such as joints, muscles and tendons) and dysmenorrhea. Moderate pain can be relieved within 1 hour after taking the medicine, and the analgesic effect can last for more than 7 hours. The curative effect on rheumatoid arthritis and osteoarthritis is similar to that of aspirin. For patients who cannot tolerate anti-inflammatory and analgesic drugs such as aspirin and indomethacin due to anemia, gastrointestinal diseases or other reasons, satisfactory results can often be achieved by using this drug.

It is safe to combine with glucocorticoid, but the effect of glucocorticoid alone is not good. The combination of this product with salicylic acid drugs is not better than salicylic acid alone. In addition, aspirin can accelerate the excretion of this product.