Asarum is slightly toxic, so the clinical dosage should not be too large. Asarum should not be taken as a single flavor or in powder form (3G) for oral administration. If it is used as a decoction, it does not need to be limited to this. After boiling Asarum for 30 minutes, the content of its toxic component safrole can be greatly reduced, which is not enough to cause poisoning.

Adverse reaction mechanism

Asarum volatile oil contains toxic components, which can directly act on the central nervous system, first exciting and then inhibiting. The suppression of the respiratory system gradually reduces voluntary movements and respiratory movements, and the reflexes disappear. Finally, breathing is completely paralyzed and stops before the heartbeat.

Adverse reactions are mainly poisoning reactions: headache, vomiting, chest tightness, shortness of breath, restlessness, stiff neck, hair standing on end, thirst, increased pulse rate, body temperature and blood pressure, dilated pupils, and flushed complexion. , muscle tremors, and body tension. If not treated in time, it can quickly turn into a spastic state, resulting in confusion, trismus, opisthotonus, twitching of limbs, exophthalmos, coma, and finally death from respiratory paralysis.

Treatment and rescue

(1) Induce vomiting immediately after poisoning, wash the stomach with 1:4000 potassium permanganate, take egg white, milk or general antidote, and add vitamins to the intravenous infusion C.

(2) Symptomatic treatment:

1) When there are symptoms such as convulsions and spasms, diazepam or Angong Niuhuang Pills can be given.

2) When anuria occurs, catheterization or oral administration of double gm is required.

(3) Traditional Chinese medicine treatment:

1) Traditional Chinese medicine for catharsis can use 9g of Citrus aurantium, 9g of Magnolia officinalis, 9g of Acorus, 9g of Glauber's salt (infusion), 15g of rhubarb (in the lower part), Decoction 2 times together, once every 4 hours, take 2 times.

2) When you have difficulty breathing, use 15g of lobelia, 15g of tea, and 9g of licorice, decocted in water for 2 times, combined together, and taken once an hour for 2 times.

3) When unconsciousness or coma occurs, take 1 Angong Niuhuang Pill, add 50 ml of water, and feed through the nose.

4) Apply the Fuzheng antidote: 3g American ginseng (decoction first), 3g Schisandra chinensis, 9g Ophiopogon japonicus, 24g raw gypsum, 30g raw licorice, 3g antelope horn powder (consumption), add mung bean soup, ** *Fry to 300ml and feed through the nose.

5) Continue to use for detoxification after waking up: 15g honeysuckle, 15g forsythia, 12g gypsum, 3g American ginseng powder (drink), 30g raw licorice, 9g raw rehmannia glutinosa, 9g paeonol bark, boil in water until 400ml, divide Take 2 times in the morning and afternoon.

Or use mung bean soup (boil until the skin opens) and 30G of raw licorice and decoct in water