(1) compound sulfamethoxazole (compound sulfamethoxazole) sulfonamides. Take 2 tablets each time, twice a day for 4 ~ 6 weeks. It has been reported that its curative effect is not good, mainly because the pH value of prostatic fluid in patients with chronic prostatitis increases, which leads to the change of plasma-prostate pH value gradient, which leads to the non-ionic back diffusion of drugs into plasma, and the drugs in prostate can not reach the bactericidal concentration. It is suggested to use it for a long time, or as a maintenance drug, so as to take effect after the pH value of prostatic fluid drops.

(2) erythromycin macrolide antibiotics. Strong ability to penetrate prostate epithelium, strong antibacterial ability in weak alkaline environment, high degree of dissociation in acidic environment, difficult to reflux back to plasma, and maintain high drug concentration in prostate. Sensitive to gram-positive bacteria, ineffective to gram-negative bacteria, sensitive to ureaplasma urealyticum and chlamydia. It is suggested to be used as an early shock drug, but it should be used in combination with drugs sensitive to gram-negative bacteria. Ureaplasma urealyticum and chlamydia can be selected as suspected pathogenic factors. Usage: 0 each time? 25g, taken orally, four times a day for 2-3 weeks.

(3) Amikacin aminoglycoside antibiotics. Although only a small amount enters the prostate, it is sensitive to gram-negative bacteria, so it has synergistic effect and is often used in combination with erythromycin. Usage: 0 each time? 2 grams, twice a day, intramuscular injection, stop taking medicine after 10, and use again after 1 0.

(4) Rifampicin has broad-spectrum antibacterial effect, which is effective for some viruses, chlamydia and anaerobic bacteria. Usage: 0 every day? 45~0? 6 g, taken continuously for 15 days, and then changed to 300 mg per day, taken continuously for 105 days. It is often necessary to cooperate with sulfanilamide synergist to pay attention to its toxicity to the liver.

(5) Quinolones have the characteristics of broad spectrum and strong efficacy, especially for Gram-negative bacteria, Neisseria gonorrhoeae and Chlamydia trachomatis. Commonly used drugs are: norfloxacin (norfloxacin), ofloxacin, ciprofloxacin (6) minocycline (minocycline) 65,438+000 mg/adult, twice a day, 4-6 weeks for 1 course of treatment.

All drugs should be used under the guidance of a specialist and adjusted in time according to the changes in the condition.