The first symptom of most patients with advanced liver cancer is pain in the liver area, and the incidence rate is above 50%. The pain in the liver area is generally located under the right rib or xiphoid process, and the pain is intermittent or persistent dull pain.

2. Symptoms of digestive tract

I want to fall down and eat my stomach after dinner. Heating, dyspepsia and nausea are common digestive tract symptoms of liver cancer, among which loss of appetite and abdominal distension are the most common.

3. fever

A considerable number of patients with liver cancer will sweat and have fever. Fever is mostly moderate to low fever, and a few patients may have high fever, which is above 39℃ and is generally not accompanied by chills.

4. emaciation and fatigue

Patients with liver cancer often feel more tired than patients with other tumors, which is similar to patients with chronic hepatitis. The cause of fatigue is unknown, which may be due to digestive dysfunction and nutrient absorption disorder, or liver cells are damaged, liver function declines, so that metabolic disorder and some toxins cannot be inactivated in time, or liver cancer tissue necrosis releases toxic substances.

API-specific biological immunotherapy mainly relies on patients' own immune cells for tumor treatment. The peripheral blood mononuclear cells of patients were collected by biotechnology, and the cells were isolated, induced, proliferated and activated in a high-level GMP laboratory. Active immune cells, passive immune cells and other immune cells (LAK cells, CD3AK cells, CIK cells, NK cells, NKT cells, TIL cells, DC cells, macrophage γδT cells, TC cells, T cells, etc. ) has high activity, quantity and tumor killing ability, and these immune cells are organically combined according to the patient's condition and reinfused into the patient for many times, and all kinds of immune cells are effective.

At present, Beijing 304 Hospital is carrying out API-specific biological immunotherapy.