The general effects of Ganoderma lucidum tablets are:
1. Ganoderma lucidum tablets prevent hypertension
Ganoderma lucidum tablets can lower the blood pressure of patients with hypertension and improve their health. Subjective symptoms, especially synergism with conventional antihypertensive drugs, make blood pressure easier to control, increase capillary loop density, diameter and red blood cell flow rate, and reduce blood viscosity. Microcirculation improves.
Ganoderma tablets can prevent and treat diabetes. Ganoderma tablets can protect and repair insulin cells, enhance insulin secretion, increase plasma insulin levels, accelerate grape metabolism, lower blood sugar, and can also enhance the hypoglycemic effect of hypoglycemic drugs.
2. Anti-aging effects of Ganoderma lucidum tablets
Pharmacological effects:
Mainly include enhancing the inhibitory function of the central nervous system, strengthening the heart, improving coronary circulation, and reducing Blood lipids, lowering blood pressure, lowering blood sugar, inhibiting platelet aggregation, enhancing immune function, anti-aging, protecting liver and relieving cough, phlegm and asthma.
1. Enhance the inhibitory function of the central nervous system: Ganoderma lucidum can inhibit the spontaneous activities of mice, prolong the sleep effect of pentobarbital sodium, strengthen the anesthetic effect of pentobarbital sodium, and strengthen the sedation of chlorpromazine. It can antagonize the central excitatory effects of amphetamine and resist nicotine-induced convulsions in mice. Electrical stimulation method or hot plate method in mice proves that Ganoderma lucidum has analgesic effect. And it can enhance the learning and memory ability of animals.
2. Cardiotonic effect: Ganoderma lucidum has obvious cardiotonic effect on isolated frog hearts and hearts inhibited by sodium pentobarbital. Intraperitoneal injection of 3g/kg can also enhance the myocardial contractility of rabbits in situ, increasing the contraction amplitude by 41.08%. Intravenous infusion into anesthetized cats also has a cardiotonic effect and slows down the heart rate.
3. Improve coronary circulation: Dog or cat coronary sinus intubation method shows that Ganoderma lucidum can increase coronary blood flow by 62%, making coronary blood flow resistance and myocardial oxygen consumption significant. reduce. While increasing the cat's coronary flow, cerebral blood flow also increases. Ganoderma lucidum can dilate coronary arteries, resist coronary artery contraction caused by pituitaryin, increase the ability of myocardium to absorb 86Rb, and increase cAMP levels in myocardial tissue, suggesting that Ganoderma lucidum can increase myocardial nutritional blood flow and improve myocardial microcirculation.
4. Lowering blood lipids and blood pressure: For rabbits with experimental hyperlipidemia, 7.5g/kg of Ganoderma lucidum can be administered intragastrically for 10 days to significantly reduce cholesterol, triglycerides and β-lipoprotein. If the Ganoderma fermentation concentrate is taken orally at 1.6ml/kg for 10 weeks, it can delay the formation of early atherosclerotic plaques. Ganoderma lucidum has obvious antihypertensive effects on a variety of anesthetized animals. After oral administration for 3 hours, the antihypertensive effect is most obvious, and its antihypertensive effect is related to the obvious inhibition of the activity of angiotensin-converting enzyme.
5. Lowering blood sugar: (1) Ganoderma spore powder extract has a preventive and therapeutic effect on diabetic mice caused by alloxan, and can antagonize the increase in blood sugar in normal mice caused by intraperitoneal injection of glucose or epinephrine. Improve glucose tolerance in diabetic mice and reduce water consumption in diabetic mice. (2) Ten minutes after taking Ganoderma lucidum orally, the blood glucose content was significantly lower than that of the control group, but the insulin level was also lower than that of the control group. Based on this, it is speculated that the principle of Ganoderma lucidum lowering blood sugar is to promote the utilization of glucose by tissues, and its blood sugar-lowering effect The ingredient is GanoderanB. 6. Inhibition of platelet aggregation: (1) Ganoderma tablets inhibited platelet aggregation induced by adenosine diphosphate or collagen to varying degrees after 1 week in 10 male patients. In vitro experiments on 14 cases showed that after injection of Ganoderma lucidum at 0.25, 0.5, and 1.0 mg/ml, rabbit platelet aggregation induced by collagen and adenosine diphosphate also showed varying degrees of inhibition. The inhibitory effect is dose-related, and while reducing the maximum collagen-induced platelet aggregation rate, it can also slow down the aggregation rate. (2) Experiments have shown that taking Ganoderma lucidum extract orally can resist the formation of platelet thrombosis and fibrin thrombus in rats, and can improve the deformation ability of aging red blood cells in the human body.
7. Enhance immune function: (1) Increase peripheral leukocytes and enhance the function of the reticuloendothelial system. Experiments have shown that Ganoderma lucidum polysaccharide can significantly antagonize the leukopenia in mice caused by cyclophosphamide at doses of 200 and 400 mg/kg per day by intragastric administration and 5 and 10 mg/kg by intraperitoneal injection per day for 8 consecutive days. pick up. It has a significant activating effect on the phagocytic function of the reticuloendothelial system.
When Ganoderma lucidum is administered by gavage or intraperitoneal injection, the phagocytosis and clearance of colloidal inert carbon particles in the blood of immunocompromised mice is significantly enhanced. The intensity of the effect has a certain dose-dependent relationship and increases with the dose. (2) Regulate immune function. Mice were continuously injected intraperitoneally with large doses of Ganoderma lucidum polysaccharide (2, 4 mg/mouse) for 5 days, which inhibited the proliferation of T cells, the induction of interleukin (IL-2) by T cells, and the production of hemolysin antibodies by B cells; when the appropriate amount Continuous intraperitoneal injection of Ganoderma lucidum polysaccharide (0.05, 0.1mg/mouse) into mice for 5 days can significantly enhance the above immune indicators. It shows that Ganoderma lucidum polysaccharide is a biological response regulator, and an appropriate amount can enhance the body's cellular and humoral immune functions. (3) The crude polysaccharide isolated from the fruiting body of Ganoderma lucidum also has an immune-promoting effect, enhancing the phagocytosis function of macrophages in normal mice and immunosuppressed mice, improving the body's resistance to harsh environments, and improving the body's tolerance to hypoxia. . Crude polysaccharide can also increase the cytochrome P450 content of mouse liver homogenate, significantly increase the proliferation of spleen T cells, and reduce the inhibition of mouse cell proliferation by cyclophosphamide. (4) Ganoderma lucidum can also increase the level of immunoglobulin IgA, increase the number of hemolytic plaques in the spleen of mice, and increase the rosette formation rate. It can promote the T lymphocyte proliferation response activated by PHA within a certain range on human T lymphocytes. Ganoderma lucidum can also inhibit the release of allergic mediators and resist the occurrence of allergic reactions. (5) Ganoderma lucidum can promote the production of interleukin II and interferon (IFNr) by lymphocytes in the elderly and enhance the activity of NK cells.
8. Anti-aging: Ganoderma lucidum can significantly extend the life span of silkworms and the average life span of fruit flies, but has no obvious effect on their maximum life span. Ganoderma lucidum can significantly reduce the mortality of mice irradiated with lethal amounts of radioactive cobalt. Although Ganoderma lucidum administered after cobalt irradiation cannot resist the lethal effect of radioactive cobalt, it can significantly extend the average survival time of animals. Ganoderma lucidum can improve the ability of animals to tolerate hypobaric and normal pressure hypoxia, reduce oxygen consumption and mortality, and significantly extend their survival time. It can also increase the survival rate of scalded animals by 2.8-4 times. It also has a stable protective effect on the myocardial mitochondria of scalded animals. Can increase cAMP levels in plasma and myocardial tissue.
9. Liver protection: Ganoderma lucidum can significantly reduce liver damage in animals caused by carbon tetrachloride and reduce blood sGPT and triglyceride levels. It can reduce fatty liver caused by ethionine, improve the detoxification ability of the liver, promote the regeneration of liver cells, and promote the speed of liver synthesis of serum albumin and nucleic acid metabolism. Taking Ganoderma lucidum polysaccharide for 7 days can promote the incorporation of 3H leucine into protein, which increases the speed of liver synthesis of serum protein.
10. Antitussive, expectorant, and antiasthmatic: Ganoderma lucidum has certain antitussive, expectorant, and antiasthmatic effects on experimental animals. The mice were treated with ammonia mist to induce cough, the phenol red secretion method, and the guinea pig group. Confirmed in experiments using amine spray method. It can also promote the resolution of inflammatory exudation in the rat chronic bronchitis model, as well as the regeneration and repair of bronchial mucosal epithelium and the recovery of tracheal cartilage deformation. And it has obvious antispasmodic effect on the contraction of bronchial smooth muscle.
11. Anti-ulcer: Ganoderma lucidum has a significant protective effect on stress and pyloric ligation ulcers, promotes the healing of acetic acid chronic gastric ulcers, and can resist the gastric juice secretion effect of pilocarpine. The anti-ulcer effect of Ganoderma is achieved by inhibiting the excitability of the vagus nerve and inhibiting gastric acid secretion.
Ganoderma lucidum tablets can delay the decline of immune function caused by aging. The earliest and most obvious feature of immune function aging. The antioxidant and free radical scavenging effects of Ganoderma lucidum tablets are also related to the anti-aging effect. Lipid peroxidation and excessive free radical production can lead to the aging of cells, tissues and organs.