Forest encephalitis is an acute infectious disease of the central nervous system caused by tick-borne encephalitis virus in flavivirus, and ticks are its transmission vector. The main clinical manifestations are sudden high fever, headache, disturbance of consciousness, meningeal irritation and paralysis, often with sequelae and high mortality. The disease is a natural focus disease in forest areas, which is prevalent in primitive forest areas in northeast and northwest China, far east of Russia and northern forest areas of Korea. There is a strict seasonality, starting in early May, reaching a peak in June, and declining in July-August, showing a sporadic state. People are generally susceptible, and all patients have contact with forest operations. Forest encephalitis is also called tick-borne encephalitis (TBE), Russian encephalitis in spring and summer, and oriental tick-borne encephalitis.