The oral dose was 1. LD50 mice were more than 65438±00g/kg/kg body weight;

The intraperitoneal injection of rats was more than 65438 0 g/kg body weight.

2.ADI 0 ~ 0.5 mg/kg body weight (FAO/WHO, 1994).

Note: This product was reported as carcinogenic in 1968. In 1972, JECFA changed Adi's weight from 0 ~ 1.5 mg/kg to 0 ~ 0.7 mg/kg tentatively. 1976 is banned in the United States. JECFA extended the temporary ADI twice in 1978 and 1982. 1984 this ADI was made during the re-evaluation.