Cirrhosis is a common clinical chronic progressive liver disease, diffuse liver damage formed by one or more causes of long-term or repeated action. Pathohistologically, there is extensive hepatocellular necrosis, nodular regeneration of residual hepatocytes, connective tissue proliferation and fibrous septum formation, leading to destruction of the hepatic lobular structure and pseudo lobe formation, and gradual deformation and hardening of the liver to develop into cirrhosis.

One: generalized fatigue is the early symptom, the degree of which may range from mild fatigue to severe fatigue. Weight loss tends to become more pronounced as the disease progresses. A few patients have irregular low-grade fever, which is associated with hepatocellular necrosis.

Two: gastrointestinal symptoms, loss of appetite is a common symptom, nausea, occasionally accompanied by vomiting. Abdominal distension is also common, related to gastrointestinal gas, ascites and hepatosplenomegaly, etc. When the amount of ascites is large, abdominal distension becomes the most unbearable symptom for patients. Some patients have abdominal pain, mostly vague pain in the liver area.

Three: bleeding tendency, there may be gums, nasal bleeding, skin purpura, women menorrhagia, etc., mainly related to the liver synthesized coagulation factor reduction and thrombocytopenia due to hypersplenism.

Four: symptoms related to endocrine disorders, men can have hypogonadism, gynecomastia, women can have amenorrhea, infertility. Cirrhosis patients with an increased incidence of diabetes, severe hepatic hypoglycemia prone to hypoglycemia.

Fifth: portal hypertension symptoms, such as esophagogastric fundal varices rupture and cause upper gastrointestinal bleeding, manifested as vomiting blood and black stool; hypersplenism can lead to thrombocytopenia, due to anemia and skin and mucous membrane pallor.