Eating puffer fish is usually nontoxic. Generally speaking, puffer fish meat does not contain toxins, and puffer fish meat is delicious and rich in nutrients, such as unsaturated fatty acids and protein. Proper diet is helpful to supplement some nutrients for the body, promote appetite and be beneficial to human health. However, it should be noted that tetrodotoxin is mainly concentrated in the skin, viscera and head of puffer fish, and contains toxic substances such as tetrodotoxin and tetrodotoxin, which is neurotoxic and highly toxic. If accidentally ingested, symptoms such as numbness of lips and fingers may occur, moderate symptoms such as motor paralysis and numbness may occur, and severe or extremely severe symptoms may even lead to blood pressure drop, dysphagia, respiratory arrest, and even death. Therefore, when eating puffer fish, you must eat it under the cooking of a professional chef and avoid cooking other parts yourself to avoid poisoning symptoms. If puffer fish poisoning occurs, you should go to a regular hospital for timely treatment.