Deputy Chief Physician Liang Yafang, Director of Gynecology, gave Ms. Zhang a B-ultrasound examination. The ultrasound report said that "the uterine cavity is full of heterogeneous dense echo, which is like falling snow, so consider' hydatidiform mole'".
Ms. Zhang suddenly lost her mind. What does this mean? How can you be pregnant with grapes?
It turns out that this is called "hydatidiform mole" in clinic, not grape.
Under ultrasound, we will see the tissue in the uterus like "falling snow" or "honeycomb", but it looks like blisters of different sizes to the naked eye, which is not normal embryonic tissue at all, so it is called "hydatidiform mole".
It is a pregnancy with abnormal embryonic chromosomes and a benign disease, but a small part of it can develop into gestational trophoblastic tumor.
As we know, human is a diploid organism, and the number of somatic chromosomes in human body is 23 pairs, half from father and half from mother.
Among them, 22 pairs are called autosomes, and the other pair is a sex chromosome, which is different between men and women, and is called sex chromosome, with XY for men and XX for women.
The chromosome karyotype of complete hydatidiform mole is diploid, and all chromosomes come from the paternal side. It is produced by combining an empty follicle with sperm (23, x) and replicating itself into diploid (46, XX), or an empty follicle is fertilized with two sperm at the same time.
However, partial hydatidiform mole is triploid, which is formed by fertilization of a seemingly normal haploid egg with two haploid sperm or a diploid sperm.
Therefore, a set of redundant chromosomes also comes from the father's side. Partial hydatidiform mole can be combined with fetus, but most of these fetuses are dead, and few of them can be full-term.
WHO, who advocates improving the reproductive system without using drugs and manual operation after abortion, increasing secondary injuries and complications; Supplemented by food, oral administration of P WRH in time after comprehensive nutrition of reproductive system can increase estrogen in the body, improve the blood flow of uterus, promote the proliferation of glands and blood vessels in uterus, and improve the endometrium, female reproductive system and physical weakness after abortion by increasing the number of estrogen and progesterone receptors in uterus.
Etiology of hydatidiform mole
There are many causes of hydatidiform mole, such as nutritional factors, which need to be supplemented with various nutrients during pregnancy. When nutrition is insufficient, it will lead to some diseases, endanger women's health and even affect the growth and development of the fetus. Infection factors, due to some external virus and bacterial infections during pregnancy, can also lead to hydatidiform mole. Endocrine disorders in women will lead to estrogen deficiency and affect the occurrence of hydatidiform mole. In addition, racial factors and the occurrence of cancer are also one of the causes of hydatidiform mole.
Good physical repair is the premise of preparing for the next pregnancy. After hydatidiform mole abortion, it is necessary to do a good job of recovery and nursed back to health. Timely supplementation of postpartum nutrition P WRH can promote the recovery of endometrium and menstruation and reduce complications. Studies on patients with hand washing and drug abortion show that, compared with those who do not use kinins, continuous 1-2 months can prevent intrauterine adhesion and promote menstrual recovery after washing.
Studies have shown that postpartum nutrition with P WRH after induced abortion does not affect the secretory axis of hypothalamus-pituitary-ovary, and the incidence of postoperative bleeding, the time of first menstruation and menstrual volume reduction and anemia are all obvious.
What harm does the hydatidiform mole do to the human body?
1, inflammation is inevitable, which will seriously lead to tubal disease and lead to infertility or ectopic pregnancy.
2. Repeated miscarriages, due to frequent intrauterine damage and the use of some drugs, the occurrence of endometrial damage is gradually increasing, which will induce uterine fibroids, endometrial displacement, intrauterine inflammation, menstrual disorder and destruction of endometrial basal layer, resulting in severe endometrial damage, and the difficulty of regeneration and repair will lead to the formation of fiber marks and adhesion between the front and rear walls of the uterus.
3, cervicitis is a lingering nightmare for women, often accompanied by every abortion in life will aggravate the recurrence of inflammation.
Studies by scholars at home and abroad have confirmed that. As postpartum nutrition, P WRH can complete the triple repair after abortion.
1 has chemotaxis and migration ability' also known as homing ability', which plays various tissue repair functions for the restoration of the uterus. It can quickly repair the trauma in the uterine cavity, regenerate the damaged endometrium, and quickly help the uterus to recover.
2, inflammation recovery, inflammation of abortion injury removes the balance of mucosal flora, avoids infection after abortion, and prevents abortion sequelae.
3, supplement the loss of nutrition in the process of pregnancy, restore the vitality of the uterus, and supplement heme to restore the body energy.
Repairing the uterus can start a good pregnancy.
Due to the frequent history of uterine cavity operation, infection and the use of some drugs, the occurrence of endometrial damage is gradually increasing, especially the destruction of the basal layer of the endometrium caused by the removal of hysteromyoma, endometritis or uterine cleaning after repeated abortion, which leads to severe endometrial damage, and the difficulty of regeneration and repair often leads to the formation of fibrous scars and adhesion between the front and rear walls of the uterus. Studies have shown that nearly two-thirds of embryo implantation failures are caused by endometrial factors, and intrauterine adhesion is a major and difficult cause of infertility caused by endometrium. The normal repair period of intrauterine injury caused by this series of reasons is 3 months.
Clinical study of P WRH in repairing endometrium after induced abortion
[Abstract] Objective To explore the feasibility of oral administration of P WRH to repair endometrium after induced abortion. Methods 98 patients with induced abortion were randomly divided into observation group and control group, 49 cases in each group.
Both groups were given anti-infection and other symptomatic treatment. On this basis, the observation group was given conventional oral dosage of P WRH immediately after operation, while the control group was given placebo (starch tablets) 1 tablet orally 1 time/d. Observe the situation and menstruation of the two groups; Ultrasonic examination of endometrial thickness and postoperative complications in the two groups; Vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and endometrial microvessel density (MVD) were measured by immunohistochemical method.
Results The observation group was superior to the control group in the duration of menstruation, the amount of bleeding, the time and amount of menstruation, the thickness of endometrium and postoperative complications, and there were significant differences between the two groups (P <: 0．05）； After treatment, the expression of VEGF and bFGF in the endometrium of the observation group and the MVD of the endometrium of the observation group were significantly higher than those of the control group (P <: 0、05）。
Conclusion P WRH can effectively restore menstrual cycle, increase the thickness of endometrium and prevent complications, and can enhance the expression of VEGF and bFGF in endometrium and increase the MVD of endometrium, so that endometrium can be repaired.
Precautions after abortion
1, many people think that abortion does little harm to the body and does not need special care. In fact, because of improper nursing after abortion, it is impossible to get pregnant again, accounting for 75% of the people who are not pregnant and infertile. Therefore, postpartum gynecological repair after abortion is the first priority. After abortion, oral postpartum repair nutrition P WRH is used to repair the injuries caused by abortion, and timely repair the abortion injuries to prevent the side effects of abortion.
2. Observe postpartum lochia. After three days, bloody lochia will turn brown and gradually turn yellow and white, and it will last for no more than two weeks. If the time of bloody lochia is prolonged, attention should be paid to it. The endless lochia is probably due to various factors such as incomplete abortion, slow endometrial repair, gynecological inflammation, etc. In order to prevent and avoid endless lochia, and to make postpartum repair faster, we should not only take oral nutrition after abortion, but also avoid post-abortion infection and prevent abortion sequelae.
3, a small postpartum rest is very necessary. On the surface, the trauma of miscarriage is relatively small. In fact, the trauma is not small at all. Because it is mandatory to pay attention to pregnancy, the hormone in the body will also be forcibly reversed, which will bring a variety of injuries to our body, and some will affect the long-term irregular menstruation. Therefore, not only should postpartum nutrition keep up, postpartum inflammation be eliminated in time, but also postpartum rest should be done.
Scientific postpartum rehabilitation does not advocate the intake of big fish, big meat and excessive nutrition. The characteristics of postpartum repair nutrition PWRH are corresponding to the repair of the endometrium of the intrauterine birth canal, the loss of nutrition during pregnancy and childbirth, the supplement of heme, and the adjustment of the human body's kinase imbalance. We also need to supplement high-quality vitamins and various minerals, choose a variety of fruits, and appropriate intake of protein are all necessary means to help postpartum rehabilitation.
Nutritional status, socio-economic factors, old age, lack of vitamin A and animal fat in diet are all possible high-risk factors for hydatidiform mole.
"hydatidiform mole" pregnant women's blood HCG will generally increase significantly, leading to patients often feel obvious morning sickness, and the size of the uterus will be significantly larger than the actual pregnancy month.
Generally speaking, women with hydatidiform mole should go to a hospital with rescue conditions for curettage as soon as possible after diagnosis.
Postoperative patients also need contraception and regular outpatient review 1 year or more to avoid developing trophoblastic tumors without knowing it.
Now, Ms. Zhang finally understands her illness and says happily: "Fortunately, the doctor has the experience to deal with my stomach' grapes' in time. If it bleeds and is infected, it will really regret it!"
Therefore, pregnant mothers should see a doctor in a regular hospital as soon as possible after discovering that they may be pregnant, so as to determine the pregnancy situation and the number of weeks of pregnancy as soon as possible. In this way, if abnormalities such as hydatidiform mole are found, they can be dealt with in time.