There is an alkaloid in puffer fish called tetrodotoxin, which paralyzes people's nerves, and finally the heart will stop beating and die. If you want to remove the tetrodotoxin from puffer fish, it will be difficult to remove the tetrodotoxin. Let's say use fire. Generally, heating can't destroy tetrodotoxin. It takes about 2,200 C to decompose the toxin.

The toxic component of puffer fish is tetrodotoxin, which is a neurotoxin. People can die if they eat 0.5mg-3mg of dolphin poison. The liver, spleen, kidney, ovary, testis, eyeball, skin and blood of puffer fish are all toxic. Eggs, ovaries and liver are the most poisonous, followed by kidneys, blood, eyes and skin. The toxin is heat-resistant,100℃ will not be destroyed for 8 hours, 120℃ 1 hour, and neither salt curing nor sun exposure can destroy the toxin.