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The two major anti-inflammatory drugs in the world: amoxicillin and cephalosporins. Do you understand their differences and applications?

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As the two top anti-inflammatory drugs in the world, amoxicillin and cephalosporin are very helpful to our body. I have an anti-inflammatory and antibacterial drug. It protects our body to be healthier.

So what are the differences between these two drugs? How should we correctly choose which drug is the best when a disease occurs?

Before talking about the differences, let’s clarify some basic concepts. Amoxicillin is a separate drug, a semi-synthetic penicillin, and a broad-spectrum β-lactam antibiotic; Cephalosporins refer to cephalosporins. This is a big concept. In terms of generation alone, there are 1, 2, 3, and 4 generations of cephalosporins. Each generation contains various different drugs. In terms of mechanism, Cephalosporins also belong to the β-lactam antibiotics. They work by destroying the cell wall of bacteria and can kill bacteria during their reproduction period.

So these drugs are all β-lactam antibiotics, and their mechanism of action should be the same. Why are there so many different drugs?

In fact, the main difference is The antibacterial spectrum of action is different. This antibacterial spectrum can be understood as the type of bacteria that the drug can effectively target. Penicillin is a broad-spectrum antibiotic and has a relatively wide range of targets.

As for cephalosporins, it depends on which generation of cephalosporins it is. The generation number of cephalosporins does not mean that the higher the number, the more advanced it is. The several generations of cephalosporins here are based on the antibacterial spectrum and nephrotoxicity. The difference is that the higher the generation number, the better. For Gram-positive bacteria, the first-generation cephalosporins are the best. On the contrary, for Gram-negative bacteria, the first-generation cephalosporin is the best. It is said that the best results can be obtained by using 4th generation cephalosporins, while the 2nd and 3rd generation cephalosporins in the middle are in between, both of which have both effects.

Therefore, it is difficult for the public to make the right choice as to what type of antibiotics are needed under what circumstances and whether to use antibiotics.

First of all, the concepts of the two are different. Amoxicillin belongs to a broad-spectrum antibacterial drug of the penicillin class, while cephalosporins are a general term for a class of antibacterial drugs. Conceptually speaking, cephalosporins are a large class of drugs, and amoxicillin is a specific drug. Amoxicillin does not belong to the cephalosporins, but to the penicillins, which are chemically similar to cephalosporins. Penicillins and cephalosporins each include many types of drugs.

Both penicillins and cephalosporins can kill bacteria, but each species kills different types of bacteria. Amoxicillin is a broad-spectrum penicillin antibiotic that kills many types of bacteria, but it cannot be used to treat infections caused by all types of bacteria.

When using antibacterial drugs, you should try to choose drugs that are targeted to specific bacteria, that is, antibacterial drugs to which bacteria are sensitive.

Secondly, a skin test is required for the use of penicillins, but there is no mandatory requirement for the use of cephalosporins. Therefore, amoxicillin belongs to the penicillin class and should be avoided if you are allergic to penicillins. Finally, the use of antibacterial drugs may cause resistance, so try to avoid using antibacterial drugs if there is no infection, and try to choose targeted antibacterial drugs when there is infection.

Amoxicillin is a broad-spectrum antibiotic with strong antibacterial effect against Gram-negative bacilli. It is mainly used for the treatment of respiratory tract, urinary tract, biliary tract and other infections caused by sensitive bacteria and the treatment of typhoid fever. It is also used for the treatment of Helicobacter pylori. Bacillus has a strong effect and can be used in combination with other drugs to treat chronic active gastritis and peptic ulcer.

Cephalosporins are divided into four generations in medicine based on their antibacterial spectrum, stability and nephrotoxicity.

The first generation, cefradine, cefathiamidine, cefazolin, etc., are more effective against Gram-positive bacteria than the second and third generations, and are effective against Streptococcus and Staphylococcus aureus.

The second generation, cefuroxime, cefaclor, etc., are similar to or slightly worse than the first generation against Gram-positive bacteria, but have obvious effects on Gram-negative bacteria and are nephrotoxic. It is lower than the first generation.

The third generation, ceftriaxone, cefixime, etc., are not as effective against Gram-positive bacteria as the first and second generations, but are effective against Gram-negative bacteria and are basically non-toxic to the kidneys.

The fourth generation, cefixime, cefepime, etc., are highly effective against most Gram-negative bacteria and some Gram-positive bacteria. Cefixime has strong anti-Pseudomonas aeruginosa. Bacteria active, more stable to β-lactamase, and non-nephrotoxic.

The harm caused by diseases is also relatively large. In normal times, we must understand the properties of some drugs before we can treat the diseases in our body. We should treat us in the correct way in normal times. Diseases in the body protect our lives, and better health is the most important. Only in this way can we restore some of the harm in our bodies, bring very healthy benefits to our bodies, and make our lives more perfect. .

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