Chinese name Hedyotis diffusa (Records of Traditional Chinese Medicine in Guangxi)
All kinds of grass
Different names of Hedyotis diffusa, Hedysarum brevicornum (Records of Traditional Chinese Medicine in Guangxi), Hedysarum ophiopogonis (Official Herbs in Southern Fujian), Phyllostachys edulis, Clerodendrum japonicum (Quanzhou Materia Medica), Clerodendrum japonicum, Hedysarum japonicum (Guangdong Traditional Chinese Medicine II), snake manager and Hedysarum japonicum.
The source is the whole grass with roots of Hedyotis diffusa, a Rubia species.
Plant-shaped Hedyotis diffusa, also known as cymbal.
Annual herb, height15 ~ 50 cm.
The stem is weak, slightly square or cylindrical, bald and hairless.
Leaves opposite, shortly stipitate or sessile; Leaf blade linear to linear-lanceolate, length1~ 3.5cm, width1~ 3mm, leathery; Stipules membranous, sheathlike at the base,1~ 2 mm long, with fine teeth at the top.
Flowers solitary or 2 in leaf axils, sessile or nearly sessile; Calyx tubular, 4-lobed, with short bristles at the edge of lobes; Corolla funnel-shaped, about 3 mm long.
Pure white, apex 4-parted, bald and clean; Stamens 4; Ovary 2-loculed, stigma 2-lobed and hemispherical.
Capsule, oblate, 2 ~ 3 mm in diameter, ventral dehiscence, persistent calyx.
The seeds are brownish yellow and extremely thick.
The flowering period is from July to September.
The fruiting period is August ~1October.
Born on hillsides, roadsides and streams.
Scattered in Yunnan, Guangdong, Guangxi, Fujian, Zhejiang, Jiangsu, Anhui and other places.
Collect in summer and autumn, dry or use fresh.
The medicinal materials are boring and all grass, twisted into a ball, grayish green to grayish brown. There is a main root, about 2 ~ 4 mm thick, and the fibrous root is slender and grayish brown. The stem is thin and curly, brittle and easy to break, with white pith in the place.
The leaves are broken, extremely stretched and easy to fall; Stipules, long1~ 2 mm.
Flowers are axillary.
Slight breath, light taste.
Location: Fujian, Guangdong, Guangxi and other places.
In Fujian and Guangxi, there are still Hedyotis diffusa users who belong to the same genus (see Hedyotis diffusa), Hedyotis filiformis (see Shrimp Grass) and Hedyotis matsudana (see Emu Tongue).
The chemical constituents in the whole plant are octadecane, stigmasterol, ursolic acid, oleanolic acid, β-sitosterol, β-sitosterol -D- glucoside, p-coumaric acid, etc.
Pharmacological effects ① Anti-tumor effect has a strong inhibitory effect on acute lymphocytic, granulocytic, monocyte and chronic granulocytic tumor cells in vitro (methylene blue test tube method); The inhibition of the first two is also strong when measured by Valsalva respirator.
The extract has been used in the experimental treatment of S- 180 and Ehrlich ascites carcinoma in mice and Yoshida sarcoma in rats, but it has no obvious anticancer effect. 0.5 ~1g crude drug/ml can inhibit Yoshida sarcoma and Ehrlich ascites carcinoma in vitro (methylene blue test tube method), but the author thinks this is non-specific.
② Antibacterial and anti-inflammatory effects The antibacterial effect in vitro is not obvious, and it only has a weak effect on Staphylococcus aureus and Shigella dysenteriae.
To observe the effect of decoction on the phagocytosis of reticuloendothelium and the phagocytosis of leukocytes in vivo and in vitro in normal and artificial appendicitis rabbits, and think that its anti-inflammatory effect is caused by factors such as comforting the proliferation of reticuloendothelium and strengthening the phagocytosis.
Sexual taste is bitter and sweet, cold.
① Records of Western Traditional Chinese Medicine: bitter and sweet in taste, warm in nature and non-toxic.
② Official Herbs of Southern Fujian: bitter, flat and non-toxic.
③ Quanzhou Materia Medica: sweet and slightly sour, cold in nature.
④ Guangdong Chinese Medicine Ⅱ: pungent, cold and non-toxic.
Meridian tropism: entering the heart, liver and spleen.
Indications-the effect of Hedyotis diffusa has the functions of clearing away heat, promoting diuresis and detoxifying.
Treat lung heat, asthma and cough, tonsillitis.
Pharyngolaryngitis, appendicitis, dysentery, urinary tract infection, jaundice, hepatitis, pelvic inflammatory disease, adnexitis, carbuncle, furuncle, snake bite, tumor.
It can also be used for digestive tract cancer.
(1) Chaozhou annals and products annals: the stem and leaf are juiced and taken, which can cure appendicitis and all intestinal diseases.
② Records of Guangxi Traditional Chinese Medicine: Treating malnutrition, poisonous snake bite and cancer in children.
External treatment of white blister sore, snake furuncle sore.
③ "Minnan Official Herbs": clearing away heat and toxic materials, diminishing inflammation and relieving pain.
④ Quanzhou Materia Medica: clearing away heat and removing blood stasis, eliminating carbuncle and detoxifying.
Treat carbuncle, sore and abscess.
It can also clear lung fire and purge lung heat.
Treating lung heat, dyspnea, cough and chest distress.
⑤ Guangxi Chinese Herbal Medicine: clearing away heat and toxic materials, promoting blood circulation and diuresis.
Treat tonsillitis, pharyngolaryngitis, appendicitis, hepatitis, dysentery, urinary tract infection and infantile malnutrition.
Usage and dosage for oral administration: decoction,1~ 2; Or mash the juice.
External use: tamping.
Should avoid "Guangxi Traditional Chinese Medicine Records": pregnant women should use it with caution.
Prescription ① Treatment of dysentery and urethritis: one or two of Hedyotis diffusa.
Decoct with water.
("Fujian Chinese Herbal Medicine") 2 Treatment of jaundice: Hedyotis diffusa one to two.
Take juice and honey.
(Xiamen) ③ Treatment of acute appendicitis: Hedyotis diffusa two to four Liang, Ranunculus japonicus one to two Liang, Zanthoxylum nitidum root San Qian.
Decoct with water.
(Guangdong "Selected Prescriptions of Chinese Herbal Medicine") ④ Treating children with fever and unable to sleep: take a tablespoon of fresh snake tongue juice.
("Minnan Official Herbal Medicine") ⑤ Treatment of sores, swelling and heat pain: Wash the fresh snake tongue, mash it and apply it, and change it when it is dry.
("Minnan official herbs") 6 Treatment of poisonous snake bites: one to two fresh Hedyotis diffusa.
Mash the juice or decoct it in water, and apply the residue to the wound.
(Fujian Chinese Herbal Medicine)
Clinical use ① Hedyotis diffusa injection for the treatment of pneumonia in children, with 2ml intramuscular injection each time (containing 4g of ineffective ingredients of crude drugs), and the infant is halved, twice a day, with a course of treatment of 5-7 days.
Treatment 1 12 cases, recovery in 52 cases, near recovery in 25 cases, deterioration in 17 cases, effective 12 cases, and death in 6 cases, with an average hospitalization of 7.98 days.
Children should reduce it.
Severe symptoms can be increased to 2 ~ 3.
Generally, patients with severe abdominal distension should be treated with water needle or new needle, and those with severe poisoning symptoms should be treated with rehydration and fasting.
After treatment 19 cases were all cured, including 3 cases of acute appendicitis 12 and appendiceal abscess. After taking the medicine for 8 ~ 9 days, the fever was reduced in10.9 days and 3.3 days.
Symptoms and signs disappeared in 3.2 days and 6 days.
1 case recurred after 4 months of cure, and was still cured by different methods.
It has been reported that fresh whole grass is decocted with 4 Liang (dry product1~ 2 Liang) and daily1~ 2 doses; Or make 100% injection for intramuscular injection, 2ml each time, twice a day, 6 hours for severe cases 1 time.
More than 50 cases of various types of appendicitis (including acute appendicitis, subacute appendicitis and appendicitis perforation complicated with peritonitis) were treated. The clinical symptoms disappeared after 2-3 days of common medication, and they recovered and were discharged every week.
Among them, acute appendicitis is the best.
The curative effect of decoction is better than that of injection.
It is also reported that 30 cases of acute and chronic appendicitis were treated by decoction, and Hedyotis diffusa was used only for simple patients with mild symptoms and discharged from hospital within1~ 2 days. For those with severe symptoms and distinct systemic and partial symptoms, spora lygodii, wild chrysanthemum or eucalyptus leaves are used together.
Except for 2 cases of chronic appendicitis who were discharged from hospital for surgical treatment, they all recovered.
The average hospitalization was 4.2 days.
③ Treatment of accessory epididymal stasis after vasectomy Based on the common spermatic cord blockade and Chinese and Western medicine treatment, the curative effect can be improved by adding Hedyotis diffusa (decocted twice a day/kloc-0, usually for 3-4 weeks as a course of treatment, and the longest time is 1 0 weeks or more); Especially for simple epididymal stagnation, the effect is more distinct.
Preliminary observation 19 cases, all of them have been treated with various treatments, such as spermatic cord occlusion, physical therapy, intramuscular injection of chymotrypsin, painkillers, new needles, traditional Chinese medicine, antibiotics and hormones, etc. Among them, 6 cases have undergone vasectomy, 1 case has undergone unilateral epididymal resection, and 2 cases have undergone painful nodule resection, and the results are not satisfactory.
After adding Hedyotis diffusa, 3 of the 10 cases of simple stasis disappeared completely, the accessory testis became soft, and the tenderness increased or disappeared; Symptoms worsened in 7 cases, and the tenderness of accessory testis increased; 9 cases were complicated with spermatic cord and epididymal inflammation, of which 6 cases worsened and 3 cases were effective.
It is thought that Hedyotis diffusa can inhibit spermatogenesis, aggravate epididymal stagnation and eliminate inflammation, so it can receive therapeutic effect.
However, the curative effect is not good for cases such as adhesion of spermatic cord and granuloma of accessory testis.
(4) Take 5 yuan of this product for treating poisonous snake bites, boil it with half a catty of white wine for 3-5 minutes, remove the residue, and take it orally by 2/3 (1 2-3 times a day),1/3 for the wound.
When applying the medicine, firstly suck out the toxic blood from the wound, cover it with a sterile cotton pad after cleaning and disinfection, and then wet the dressing with medicinal liquor (to keep it moist).
If you can't drink alcohol, you can boil it with clear water, and then add excessive white wine after boiling, but it is still better to cook it with white wine.
For patients with persistent edema, serious illness and wound infection, other Chinese herbal medicines and antibiotics should be added appropriately; As for mild and moderate cases, this method alone can be used to treat them.
According to 19 cases, 3 ~ 6 doses of common medicine can recover.
⑤ For the treatment of pelvic inflammatory disease and adnexitis, Hedyotis diffusa 1.5 is used, with 3 yuan of Cerambycladus japonicus (Zanthoxylum nitidum) or 3 yuan of Dioscorea nipponica Thunb. is added and decocted in water, with a dose of/kloc-0 per day.
After 77 cases were treated, 4 cases were effective and the rest recovered.
In addition, I have tried 100% Hedyotis diffusa injection for intramuscular injection, 2ml each time, three times a day, to treat cervical cancer, gastric cancer and liver cancer 1 case, and the symptoms have been improved at different levels.
Hedyotis diffusa, Herba Artemisiae Scopariae and Herba Lysimachiae Christinae were used to prepare cholagogic mixture, which was used to treat cholelithiasis and other biliary diseases, among which 9 cases of abdominal pain, jaundice and fever were relieved within 2.2 days. In 3 patients after choledocholithotomy, after taking the medicine, the amount of bile doubled, the bile sediment was discharged a lot, and the jaundice index gradually decreased, suggesting that Lidan mixture has distinct gallbladder-promoting and calculus-expelling effects.
Note: H.corymbosa (L.)Lam and H.tenelli floraB 1 belong to the same plant, and also used as Hedyotis diffusa. Introduction to the effect of Scutellaria barbata;
Scutellaria barbata (Records of Plant Medicine in Jiangsu)
With different names, Tongjingcao, Echinochloa purpurea, Hetoucao (Nanjing Official Herbs), Toothbrush Herb (Jiangsu Medicinal Herbs Records), Little Hanxincao, Shui Han Xin (Guangxi Medicinal Plants Records), Little earpick Herb (Nanning Medicinal Herbs Records), Scutellaria baicalensis Georgi, Golden Ear (Jiangxi Official Herbs Prescription), Prunella vulgaris, and Prunella vulgaris. Trumpet to the sky, tiger bites red, regenerated grass (Fujian Chinese Herbal Medicine), mountain whip (Chengdu Handbook of Common Herbs Treatment), narrow leaves to the sky (Fujian Selected Materials of New Medical Law).
The source is the whole grass of Scutellaria barbata of Labiatae.
Scutellaria barbata in plant shape, also known as Hanxincao Diye.
Perennial herbs.
Root whisker-like.
The stem is erect, quadrangular and15 ~ 50 cm high.
Leaves opposite; Oval to lanceolate, about 7 ~ 32 mm long, 4 ~15 mm wide, truncated or heart-shaped at the base, obtuse at the apex and sparsely serrated at the edge; The leaves at the lower part of the stem have short stalks, and the leaves at the top are nearly sessile.
There are two flowers in Hua Lun, which are combined with terminal and axillary lateral racemes; Bracts lanceolate, hairy below and at the edge, glabrous on the opposite side; Petiole length1~15 mm, densely covered with mucinous pubescence; Calyx is bell-shaped, with 2 cleft lips at the top, and a shield is often attached to the back of one side of calyx tube; Corolla is light blue-purple, tubular, with 2 cleft lips at the top, helmet-shaped and 3-cleft upper lip, toothed lobes at both sides, round lobes at both ends and kidney-shaped lower lip; Stamens 4, 2 strong, not protruding; The ovary is 4-lobed, and the style is completely inserted at the bottom of the ovary and 2-lobed at the top.
Nutlets are spherical, transverse and have curved stalks.
The flowering period is from May to June.
The fruiting period is from June to August.
Health is good at wet places near ponds, fields or roadsides.
Scattered in Jiangsu, Guangxi, Guangdong, Sichuan, Hebei, Shanxi, Shaanxi, Hubei, Anhui, Jiangxi, Zhejiang, Fujian, Guizhou, Yunnan, Taiwan Province, Henan and other places.
Collect when flowering, remove roots, use fresh or dry in the sun.
The medicinal materials are dull and whole grass, and the leaves are mostly scattered. They are stems and branches with spikes, which are15 ~ 25 cm long, quadrangular, yellow-green or purple-brown in appearance, smooth, soft, fibrous and hollow in broken surface. The remaining leaves are dark yellow-green, mostly broken, stretched and curled, brittle and easy to fall; The flower spike is inserted at the branch end, yellow-green.
The smell is weak and the taste is slightly salty and bitter.
Jiangsu, Jiangxi, Fujian, Guangdong, Guangxi and other places.
Chemical components The whole plant contains alkaloids, flavonoid glycosides, phenols and steroids.
Pharmacological action The methylene blue test tube method was used to select the experiment, which had a slight inhibition on the blood cells of acute myeloid leukemia. In the selection experiment of cell respirator method, the inhibition rate of the above leukemia blood cells is more than 75%.
Sexual taste is pungent and flat.
① "Atlas of Guangxi Medicinal Plants": pungent and slightly fishy in taste, flat in nature and nontoxic.
② Annals of Medicine in Nanning: sweet, flat and nontoxic.
③ Jiangxi Official Herbal Prescription: flat in nature, slightly bitter in taste and non-toxic.
④ Handbook of Common Chinese Herbal Medicines of Guangzhou Army: slightly bitter and cold.
Indications-the effect of Scutellaria barbata on clearing away heat, detoxifying, removing blood stasis, stopping bleeding and relieving pain.
Treat hematemesis, epistaxis, bloody stranguria, dysentery, jaundice, sore throat, lung carbuncle, furuncle, scrofula, sore poison, cancer, traumatic knife injury and snake bite.
① "Nanjing Official Herbs": Breaking blood and dredging channels.
② "Guangxi Herb Plant Atlas": diminishing inflammation, removing blood stasis and stopping bleeding.
Treat falls, injuries and bloody dysentery.
③ Annals of Medicine in Nanning: detumescence and pain relief.
Treat falls, cuts, sores.
④ Quanzhou Materia Medica: clearing away heat, detoxicating, expelling wind, dispersing blood, activating qi, promoting diuresis, dredging collaterals, breaking blood stasis and relieving pain.
Oral administration for treating stranguria, vomiting blood and epistaxis; Externally used to treat snake bites, carbuncle, furuncle and nameless swelling.
⑤ Manual of Common Chinese Herbal Medicines of Guangzhou Army: clearing away heat and toxic materials.
Treating cancer can improve symptoms; Appendicitis, hepatitis
⑥ Chengdu Handbook of Common Herbs Treatment: Treating esophageal cancer, gastric cancer and uterine cancer.
Usage and dosage for oral administration: decoction, 0.5 ~12 (fresh1~ 2); Or mash the juice.
External use: tamping.
It is advisable to avoid blood deficiency, and pregnant women should take it with caution.
Prescription 1: Treatment of hematemesis and hemoptysis: fresh Hanxin grass with narrow leaves is 1-2 liang, mashed juice, mixed with a little honey, stewed in hot water twice a day.
("Quanzhou Materia Medica") 2 Treatment of urethritis, urine and blood pain: one or two fresh Hanxincao, washed, decocted, and mixed with rock sugar twice a day.
("Quanzhou Materia Medica") 3 Treatment of heat-induced bloody dysentery: Xiao Han Xin Cao Er Liang, decocted.
("Guangxi Medicinal Plant Atlas") 4 Treatment of dysentery: fresh Hanxincao with three to five taels, mashed juice; Or dry the whole grass one or two times and decoct it in water.
("Fujian Chinese Herbal Medicine") 5 Treatment of hepatitis: five yuan for fresh Scutellaria barbata and five red dates.
Decoct with water.
("Zhejiang official commonly used herbs") ⑥ Treatment of stomach gas pain: one or two dried Hanxincao, and one pig's belly or chicken (head and toes removed, internal organs removed), half boiled with water and wine for two or three times.
("Quanzhou Materia Medica") ⑦ Treatment of sore throat: eight yuan for fresh Hanxincao, eight yuan for fresh verbena, and a little salt.
Decoct with water.
("Fujian Chinese Herbal Medicine") 8 Treatment of pharyngolaryngitis and tonsillitis: Scutellaria barbata, Cornu Cervi Pantotrichum and Solidago San Qian.
Decoct with water.
("Zhejiang official commonly used herbs") 9 Treatment of lung abscess: one or two of Scutellaria barbata and one of Houttuynia cordata.
Decoct with water.
("Zhejiang official commonly used herbs") ⑩ Treatment of snakehead furuncle and lymphadenitis: fresh Hanxin grass with narrow leaves-to 22 Liang, adjust a little salt, mash it and take it orally.
("Fujian Chinese Herbal Medicine") ⑾ Treatment of scrofula: two or two pieces of Scutellaria barbata, decocted in water.
Or one or two pieces of Scutellaria barbata and water keel, add too much lean pork, cook it, and eat meat and soup.
⑿ Treatment of carbuncle on the back: fresh Scutellaria barbata roots are mashed and taken orally.
Leave a white head and apply it twice a day.
Take one or two herbs, decoct them in water and take them for four or five times to expel pus.
After discharging pus, drip the root juice into the hole and wrap it with gauze, and change it twice a day.
[13] Treatment of cancer: one or two roots of Scutellaria barbata and Ampelopsis grossedentata, four or two roots of rattan pear, two or two roots of Myrica rubra, and five dollars each of cogongrass rhizome, Pteris multifida and Lobelia chinensis.
Decoct with water.
(⑾ The official commonly used herbs in Zhejiang are listed below) (⒁ Treatment of traumatic injury: Xiao Han Xin Cao mashed it and boiled it with distiller's grains.
("Guangxi Medicinal Plant Atlas") ⒂ Treat all poisonous snake bites: fresh Hanxincao with narrow leaves, wash and mash, wring juice, mix yellow wine with a little warm clothes, and apply residue to the affected area.
("Quanzhou Materia Medica") ⒃ Treatment of poisonous snake bites: fresh Scutellaria barbata, Guanyin grass each-to two, fresh Scutellaria barbata, fresh a pack of needles each four to eight.
Decoct with water.
In addition, wash the fresh grass, add a little salt, mash it and take the juice for oral administration.
("Zhejiang official commonly used herbs")
For clinical use, take Scutellaria barbata 1 2 for cancer, decoct in water twice, and take it separately in the morning and afternoon, or replace tea.
According to the observation of 36 patients with esophageal cancer and lung cancer, some patients have improved their symptoms in the near future after taking the medicine, but no root cure effect has been seen yet.
In addition, Scutellaria barbata and Solanum lyratum Thunb. 1 two, decocted in water, daily 1 dose.
Used in lung cancer, it also has a certain effect on improving symptoms.