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The side effects of drugs are "different between men and women". What is the difference?

Since the male and female reproductive systems have different characteristics, the kidney function, metabolism and liver metabolism function are also different. Therefore, when taking the same drug, its drug metabolism and pharmacokinetics will be different. The characteristics of the drug may be different, resulting in differences in the efficacy and adverse effects of the drug. The differences between medications in men and women should be taken into consideration. Drug absorption and metabolism are associated with different characteristics of a particular disease between genders, and the risk of side effects varies.

Be careful when using medication during special periods. After all, there are always a few days every month. The differences in physiological structure mean that men and women have some special periods for taking medication. A woman's uterine lining sheds periodically, causing menstruation. There are some medications that women should avoid during their period and in the days leading up to their period. For example, hormonal drugs can affect the endocrine system, and taking them during menstruation can easily cause abnormalities in the menstrual cycle, menstrual time, and menstrual blood volume; aspirin can increase menstrual flow; anticoagulants such as coumarin, heparin, and thrombolytic agents can cause heavy bleeding. , should not be used during menstruation. In addition, vaginal suppositories should be used with caution during menstruation. After middle age, men's prostate function gradually deteriorates, and the anticholinergic effect of chlorpheniramine can cause the bladder detrusor to relax and reduce its contractility, aggravating the symptoms of prostatic hyperplasia and making urination more difficult. It is recommended that middle-aged and elderly men should use chlorpheniramine with caution to prevent its impact on the prostate.

Adjust dosage. The clearance rate of zolpidem sleeping pills from the body is significantly slower than that of men, and women are more sensitive to side effects. They have lower arousal the next day, especially the increased risk of driving in the early morning. Adjust medication intervals. The average body fat content of adult women is 16.5 kilograms, and that of men is 13.5 kilograms. Therefore, after women take fat-soluble drugs, the utilization rate is higher; studies have found that after pre-adolescent women take iron, 45 can enter red blood cells to play a role, while men can only 35. For these drugs, men can follow the doctor's advice to increase the dosage or shorten the medication interval to better exert the effect of the drugs. Women are more sensitive to pain and often need a slightly larger dose of analgesics to achieve the same analgesic effect as men. The medication intervals can be shortened under the guidance of a doctor, but they should not be used too frequently; many anticoagulants need to be combined with proteins in the body to achieve the same analgesic effect as men. It works effectively, and men usually have more muscles, so the effect of taking this kind of medicine is better. It is generally not recommended to shorten the interval between use.

Post-medication treatment. Rinse your mouth after using asthma spray, otherwise hormones may accumulate in the body for a long time. Menopausal women have endocrine changes and are prone to osteoporosis, so they need to pay more attention to this problem after taking medication. When women take birth control pills and other photosensitive drugs, they should protect themselves from the sun and try to avoid going out during times of strong sunlight. It is best to apply sunscreen and use a parasol when necessary. You should still pay attention to sun protection within 3 to 5 days after stopping taking this kind of medicine. Men should also pay attention to similar issues when using photosensitive antibiotics such as tetracycline. Only by understanding these can we live a healthier life.