We have always said that the most effective anti-aging ingredient in skin care products is vitamin A alcohol.
If vitamin C, like a warrior, goes into battle in person and dies with ROS, leading to oxidation.
Then vitamin A alcohol is more like a commander-in-chief, through signal regulation-
On the one hand, it guides the accelerated renewal of skin epidermis to make it thicker and more orderly;
On the one hand, it can also direct the dermis to accelerate the production of collagen and inhibit the destruction of collagen by MMP.
But the commander-in-chief also has many weaknesses:
Weak body (unstable, afraid of light), often sick-leading to skin irritation and allergies.
So everyone loves and hates, especially sensitive skin, and can only sigh.
And psoralen may make up for everyone's regrets:
From the mechanism point of view, the cellular signal regulation pathway of psoralen is very similar to vitamin A alcohol, including the regulation of retinoic acid receptor gene, collagen and extracellular matrix synthase.
Meanwhile, the disadvantages of vitamin A alcohol are avoided:
Psoralen has good stability and is not afraid of light at all-so it can be used during the day;
At the same time, psoralen has less side effects and less skin irritation than vitamin A alcohol-is there any hope for sensitive skin? ?
In the random double-blind test of makeup detection, one group used 0.5% psoralen twice a day, and the other group used 0.5% vitamin A alcohol once a day/kloc-0 times. After 12 weeks, the wrinkles and spots in the two groups were obviously improved, and there was almost no difference between the two groups.
In terms of side effects, the stinging and peeling phenomena in vitamin A alcohol group were significantly higher than those in psoralen group, and the itching and burning sensation were also higher than those in psoralen group.
In the fourth week, psoralen group was more prone to skin redness than vitamin A alcohol group, but there was no difference between the two groups at the eighth and twelfth weeks after continuous use.
Therefore, according to the current research, psoralen can be used as a more perfect anti-aging component than vitamin A alcohol.
I prefer to use pomelo psoralen, which was developed by Dr. Tsinghua.