Drug name: Angelica sinensis
Alias: Angelica sinensis, Dangzaogui of Yanbian, Angelica sinensis of Korea, Angelica sinensis of Yamato, Angelica sinensis of Japan.
Chinese pinyin: dong dang gui
Latin plant mineral: Angelica Acutilobakitag. [Ligusticum Acutilobum Zucc]
pharmacological action
Danggui decoction (100%) can excite the isolated uterine smooth muscle of pregnant rats in pre-estrus, and significantly increase the contraction range, with an obvious dose-effect relationship. It can obviously increase the frequency of smooth muscle contraction in isolated uterus of rats in early pregnancy, but has no obvious effect on the contraction amplitude. Angelica sinensis 3.3-66.7mg/ml can antagonize the contraction of isolated rat uterine smooth muscle induced by pituitrin in a dose-effect relationship.
Efficacy: promoting blood circulation; Regulating menstruation and relieving pain; Moisten dryness and smooth intestines
Indications: blood deficiency syndrome; Irregular menstruation; Dysmenorrhea; Menopause; Postpartum abdominal pain; Intestinal dryness constipation
Ecological environment: Japan and Korea use this species as angelica and cultivate it as medicine.
Harvest and storage:
Excavate in autumn, remove its fibrous roots, stems and leaves and impurities, put it indoors, smoke it with low fire, and then dry it.
Distribution of resources: Yanji, Hunchun and Helong in Yanbian Korean Autonomous Prefecture, Jilin Province, China are cultivated.
Efficacy classification: Huoxue drugs; Analgesics for regulating menstruation; Medicine for moistening dryness and smoothing intestine
Sexual taste: pungent; Gan; Sexual temperature
Medicinal material source: the root of Angelica sinensis, an Umbelliferae plant.
Administration and dosage: oral administration: decoction, 10-30g.
Source: "Chinese Materia Medica" plants contain polysaccharides. Angelica-pectin)A is contained in the root, and the volatile oil of the root mainly contains ligustilide, n-butylidenephthalide, cnidilide, isocnidilide, niacin and vitamin B/kloc-0. Sedanolide, folic acid0, P-cymene, β-sitosterol.
Roots and fruits contain bergapten, xanthotoxin0 (Xanthoxin 0, isopimpinellin).
The volatile components in plants include butylphthalide 0, butylphthalide and ligustilide. Character identification: root hypertrophy, length 10- 18cm. The root head and taproot are short and slightly cylindrical, with a length of 1.5-3cm and a diameter of1.5-2 cm; There are more than 5- 10 lateral roots at the lower end of the main root, which are curved in shape and vary in length, ranging from 3- 10cm in length to 0.2- 1cm in diameter. The surface is yellow-brown or brown, with irregular longitudinal wrinkles and transverse oval lenticels. The top of the taproot is flat, with a concave stem mark in the center and horizontal stripes on the surface. Brittle and easy to break, with flat section, white or yellowish white skin, many oil chambers and cracks, brown cambium ring, yellow or yellowish brown wood, many oil chambers and cracks, brown cambium ring, yellowish white or yellowish brown wood, and dense rays. Has a special fragrance. It tastes sweet and then slightly bitter and pungent.
Microscopic identification: root cross section: cork layer consists of 2-4 rows of flat cork cells. The cortex is narrow and has cracks, and sometimes a few small secretory cavities can be seen. The phloem is wide, the oil chamber is round, the one near the cambium is small, and the ray is as wide as 10 multi-row cells. The cambium is annular. Xylem vessels are single or 2-3 cells in bundles, arranged radially, and the line width of xylem is 10. The center is the primary xylem.
Powder characteristics: light yellow brown. 1. There are many starch granules, and the single granule is round or spherical, with a diameter of 4-30μm, and the umbilicus is punctate, short-slit and bird-shaped. Multiple grains are composed of 2-9 sub-grains, and the large grains are faintly layered. 2. The ducts are mostly reticulate, with a diameter of 60μm, and threaded ducts can also be seen. 3. Cork tissue fragments are light yellow and rectangular or polygonal. 4. Oil chamber or its fragments.
Physical and chemical identification: take 0.2g of coarse particles of medicinal materials, add 2ml of 70% ethanol solution into the test tube, shake immediately, shake every 10min, soak 1 h, take the supernatant, spot it on filter paper, and observe it under a second ultraviolet lamp at 254nm after drying, which shows blue fluorescence.