Duzhong Pi is an over-the-counter medicine, belongs to a kind of Chinese medicine, the flavor is calm, can nourish the liver and kidney, strengthen the tendons and bones, and tranquilize the fetus. It is mainly used for treating soreness of waist and spine, impotence of feet and knees, residual leakage of urine, wet and itchy under the yin, fetal leakage and desire for abortion, restlessness of fetus, and high blood pressure.

Middle-aged and elderly people with insufficient kidney qi, lumbar and knee pain, weak legs and feet, urinary leakage of food; women's weakness, kidney qi is not solid, fetal leakage of abortion and habitual abortion is recommended to eat to protect the fetus, the sequelae of polio, children walking too late, the two lower limbs of the weakness of the people should eat; hypertension patients should eat.

Originally from the Divine Husbandman's Classic of the Materia Medica

Category Bark.

Duzhong is synonymous with Si Xian ("Ben Jing"), Mu Mian, Si Zhong ("Bie Lu"), 檰 ("Ben Cao Tu Jing"), Shi Si Xian ("Supplement to Diffractions of the Materia Medica"), Silk Lian Bark, Silk Neem Bark ("Chinese Medicine Zhi"), Rip Silk Bark ("Hunan Drugs Zhi"), Silk Cotton Bark ("Manual of Traditional Chinese Herbs" by Su Medical), Jade Silk Bark, Rip Silk Pieces.

SourceThis product is the bark of Eucommia ulmoidesOliv.

The taste is sweet, slightly pungent and warm. ①Benjing: "Pungent in flavor, flat." ② "Bie Lu": "Sweet, warm, non-toxic."

3 "Pharmacognosy": "Bitter flavor." ④ Pungent, flat, non-toxic, regulating qi and tonifying blood. ⑤ Chinese People's **** and National Pharmacopoeia, 2010 Edition, Part I: "Sweet, warm. Attributes to the liver and kidney meridians."

Use and Dosage ①Internally: decoction, 3～5 qian; soaked in wine or in pills and powder. ②6～10g.

CollectionIn order to protect the resources, the local peeling method is generally used. Between Qingming and the summer solstice, select plants that have grown for more than 15 to 20 years, peel off the bark according to the size of the herb specification, shave off the rough skin, and dry it in the sun. The dry place is ventilated.

Pharmacological effects

①Antihypertensive effect

Extracts and decoctions of the bark have a long-lasting antihypertensive effect on animals. With its infusion of 5 ml (1 ~ 2 grams of raw drug) to the anesthetized dogs after intravenous injection produces significant antihypertensive effect, can be sustained for 2 ~ 3 hours, the phenomenon of "fast tolerance". In 3 renal hypertensive dogs, the decoction was administered daily by gavage at 5-8 g/kg for 4 weeks, and the reduction in systolic blood pressure was only 8-22 mmHg (4-10%) at most, so the efficacy of the treatment was not satisfactory. The concoction and dosage form of Cortex Eucommiae have some influence on the antihypertensive effect, the effect of decoction is stronger than that of tincture, and the antihypertensive effect of fried Cortex Eucommiae is greater than that of raw Cortex Eucommiae. Cortex Eucommia Ulmoides has antihypertensive effect on cats, but it lasts for a short period of time, and the phenomenon of "rapid tolerance" is not significant. The hypotensive effect on rabbits with cholesterol atherosclerosis is more significant than that on normal rabbits, but it can also produce "fast tolerance". As for the principle of antihypertensive effect, it is preliminary because the active ingredient has not yet been determined. It has been proved that the acute antihypertensive effect is not related to the vagus nerve and is not affected by atropine. For isolated rabbit heart, Cortex Eucommiae was first excited in small amount and then slightly inhibited; its inhibitory effect on the heart was also reported to be related to its pH (pH between 4 and 5), which was adjusted to be excitatory for isolated hearts of both rats and rabbits. Cortex Eucommiae has a direct dilatation effect on normal rabbit ear blood vessels, but the same concentration makes experimental cholesterol atherosclerosis rabbit ear blood vessels were contraction, on the normal rabbit coronary blood vessels and renal blood vessels in the low concentration of the dilatation effect, the high concentration is the opposite, on the atherosclerosis of rabbits coronary blood vessels in the low concentration of contraction was also presented. Because of the direct relationship between its antihypertensive and heart and blood vessels, it is inferred that it is central.

②Diuretic effect

All kinds of preparations of Cortex Eucommiae have diuretic effect on anesthetized dogs, and there is no phenomenon of "fast tolerance". It also has diuretic effect on normal rats and mice. Cortex Eucommia contains 0.4% potassium, so it is inferred that diuresis may be related to potassium.

③Other effects

Clinical use of Cortex Eucommiae infusion can reduce blood pressure in hypertensive patients, and improve the symptoms of dizziness, insomnia, etc. A large dose (20-25g/kg/day) of Cortex Eucommiae decoction to the dog by gavage can make it quiet, sleepy, and not easy to accept external stimuli. The large dose of Cortex Eucommiae also has the effect of inhibiting the central nervous system in mice. Cortex Eucommiae can inhibit the excitatory effect induced by the posterior pituitary of rats and rabbits on the isolated uterus and make the uterus relax, but the isolated uterus of cats is excited. Some inhibitory effects of a decoction of Cortex Eucommiae on Mycobacterium tuberculosis in the test tube have been reported. Its alcoholic infusion seems to reduce the absorption of cholesterol in the intestines of rats.

The leaves of Cortex Eucommiae contain Eucommia gum, Pinoresinol diglucoside, Kaempferol, Eucommiae glucoside, Sinequanoside, Rebutoloside, Hapagide acetate, Galactitol, and some trace elements Zinc, Copper, Iron, Calcium, Phosphorus, Manganese, and Lead.

The results of animal experiments show that eucommia can enhance the vitality of SOD in red blood cells of mice and enhance their adrenal weight. Eucommia can normalize the low physiological function, suggesting that Eucommia has certain anti-aging effect. A variety of trace elements rich in eucommia have close relationship with the structure and function of human endocrine system, immune function system, growth and development system, especially with anti-aging. For example, zinc can accelerate the repair of trauma, ulcers, surgical wounds, etc., and play a specific role in promoting cell division of lymphocytes, which indicates that zinc has a role in delaying aging.

Drug Concoction

Eucommia: remove the coarse skin, wash, moisten, cut into squares or silk strips, and dry in the sun. Salt Duchenne: first use salt with appropriate amount of boiling water to dissolve, take Duchenne block or silk strips, so that with the salt water is fully mixed through the absorption, and then placed in the pot, stir-fried to the degree of slightly burnt spots with a gentle fire, remove and dry. (Each 100 pounds of eucommia, with 3 pounds of salt) eucommia after frying, then eucommia gum is destroyed, the active ingredients are easy to decoct.

1) "Lei Gong Cannon Frying Theory": "Wherever you make Duchenne, you must first cut off the rough skin. With crisp, honey roasted. Where to repair a catty, crisp two two, honey three two, the two flavors and make a place to use."

② "Materia Medica Hook Yuan": "Cortex Eucommiae, with wine fried broken silk."

Functions and Indications

To tonify the liver and kidney, ? [1]? Strengthening the tendons and bones, and tranquilizing the fetus. Treating soreness of the waist and spine, impotence and weakness of the feet and knees, residual leakage of urine, wet itching under the yin, fetal leakage, restlessness of the fetus, and high blood pressure.

①Benjing: "Mainly for lumbar spine pain, tonifying the middle and benefiting the essence, firming the tendons and bones, strengthening the will, removing the itchy dampness under the yin and the remaining leaking of urine."

② "Bielu": "Lord feet in the soreness, do not want to trample the ground."

③ "Pharmacognosy": "treatment of kidney cold hip lumbago, waist patients weak and strong body, wind. The waist is unfavorable to add and use."

4 "Rihuazi Materia Medica": "Treatment of kidney labor, lumbar spine contracture. Into the medicine roasted with."

⑤ Wang Hao Gu: "Moistening liver dryness, tonifying wind deficiency in the liver meridian."

6 The Materia Medica Zheng: "Stopping small water dreaming, warming the uterus, and stabilizing fetal qi."

⑦ Jade Rowan Medicinal Explanation: "Benefiting the liver and kidneys, nourishing sinews and bones, and removing dampness and lust from joints. Treats soreness of the waist and knees, and contracture of the legs and feet."

8 "Materia Medica again new": "filling the tendons, strong Yang Road."

9 "Chinese People's *** and State Pharmacopoeia" (2010 version of a): "tonifying the liver and kidney, strengthening the muscles and bones, and stabilizing the fetus. It is used for insufficiency of liver and kidney, soreness of waist and knees, weakness of muscles and bones, dizziness, leakage of blood in pregnancy, and restlessness of fetus." Cortex Eucommiae is a valuable tonic herb, its active ingredients contain a large number of known active medicinal ingredients, but also contains a variety of nutrients, nutrients are the important material basis for the health effects of Cortex Eucommiae.

Justice: Cortex Eucommiae is calm in nature, nourishing the liver and kidney, all have no contraindications.

People who have a deficiency of yin and fire should be cautious of taking it.

①The Collected Notes on the Materia Medica: "Wicked snake skin and Yuan Shen."

② "Materia Medica": "Kidney deficiency fire should not be used. That is, when used with cypress, Zhimu into the same."

③ "Getting the match of the Materia Medica": "Internal heat. Essence and blood dry two prohibited."