1. Intraocular ossification
Often occurs in long-term atrophic eyes caused by trauma, inflammation or congenital developmental abnormalities, etc. CT and ultrasonography can see intraocular osseous images similar to those of choroidal osteoma, but intraocular ossification is often due to concomitant cataract or other anterior segment abnormalities of the eye and the bottom of the eye can't be detected, and the imaging can be seen as the eye axis is shorter than that of normal eyes, loss of visual acuity, and history of the disease. It helps in differential diagnosis. Histopathological examination in the metaplasia of the bone, most of the vascular components, and no choroidal osteoma seen in osteoblasts and osteoclasts, only a small number of similar to the osteoblast-like cells, the nucleus of the cells is small and condensed, suggesting that the bone itself does not have the ability to grow.
2. Choroidal hemangioma
Choroidal metastatic carcinoma, intraocular lymphoma, and non-pigmented choroidal malignant melanoma are non-mapular in shape, with smooth surface and no hilly undulation, and may be accompanied by plasmacytoid detachment of the retina, which may be differentiated from the absence of calcified spots on CT.
3. Ball wall foreign body
Often there is a history of trauma, CT and ultrasound examination of foreign body lesions is more limited, if you can see the fundus, in view of the lack of ball wall foreign body choroidal osteoma characteristic changes, can be a clear diagnosis.