Analysis: Hello, taking into account your age 49, hands and feet tingling while sleeping is very common. The reason is obvious, the night hand numbness of the situation of common diseases are cervical spondylosis, dyslipidemia, peripheral neuritis and other diseases of the situation. In addition, cerebral insufficiency of blood supply, as you said, can also be caused. Numbness of hands and feet caused by cerebral arteriosclerosis can be accompanied by dizziness, headache, memory loss, vision loss, high or low blood pressure, increased blood lipids and other changes, and this numbness of the hands and feet is semi-lateral, the patient's age; cervical spondylosis caused by numbness is the affected side of the hand or upper limb numbness, accompanied by pain, limited movement; multiple peripheral neuritis caused by numbness is the symmetric numbness of the limb ends (fingers, toes), accompanied by pain; thrombotic vasculitis can also be caused by the cerebral blood supply deficiency, but also can be caused by the cerebral arterial insufficiency. Thrombophlebitis can also cause cold toes or feet, cold, severe pain, dorsalis pedis arterial pulsation is weakened or disappeared, etc.; such as high blood pressure patients, repeated unilateral numbness of the hands and feet, should see a doctor in time to rule out pathological numbness. Opinion: Personal advice, sleep state blood circulation is slow, the heart is like a water pump to sleep when the "pump" workload is small circulation of slow, so the hand is more prone to numbness. If you sleep too well, do not turn over, there should be such a situation, generally a position for a long time, the body's blood does not flow caused by local numbness; if this is often, not sleep very well, as long as a long time on the numbness. If this is the case, then it is better to go to the hospital for a checkup. It is recommended that you turn over more often when you sleep, and do not always keep a movement. I wish you good health.