Xia Gu Cao is a traditional Chinese medicine that softens and disperses knots, and has obvious efficacy in treating lymphatic system tumors. Xia Ku Cao 《Benjing》 [synonym] Xi sentence, Nai Dong 《Benjing》, Yan face 《Bei Lu》, wheat ears Xia Ku Cao, wheat Xia Ku, iron thread Xia Ku〈Diannan本草〉, iron color grass〈Compendium〉, stick column head flower〈China medicinal plant Zhi〉, big head flower〈Zhejiang traditional Chinese medicine manual〉, lantern head, goat's intestines vegetables〈Jiangsu medicinal journal〉, white flower grass〈Hebei medicinal herbs〉, bloating full grass〈Shandong traditional Chinese medicine〉, mallet grass〈中中藥志〉, dry leaf leaves < Shaanxi Chinese medicine record〉, gong hammer grass, east wind, bullock grass, broad valley grass (Hunan medicine record〉, June dry, stick head column (east Fujian materia medica)。 [Originally] is the fruiting spike of Labiatae plant Xia Gu Cao. [Plant Origin] Prunella vulgaris L. is a perennial herb with square stems, creeping at the base, about 30 centimeters tall, densely covered with fine hairs throughout the plant. Leaves opposite, those near base stipitate, upper leaves sessile, leaf blade elliptic, lanceolate, entire, or slightly serrate. Verticillasters terminal, spicate, bracts reniform, base truncate or slightly heart-shaped, tip abruptly long caudate-acuminate, abaxially hirsute, calyx labiate, anteriorly hirsute, posteriorly glabrous, upper lip elliptic, 3-lobed, expanded into semilanceolate on both sides, lower lip 2-lobed, lobes triangular, apex acuminate, corolla purple or white, labiate, proximal portion tubular, upper lip hooded, 2-lobed, lower lip spreading, 3-lobed. Stamens 4 strong, filaments apically forked, one end bearing anthers, ovary 4-lobed, style filiform. Nutlets brown, long ellipsoid, 3-angled. Nutlets brown, long ellipsoid-protomorphic, 3-angled. Fruiting June-July. Born in wasteland, roadsides and grassy slopes. Distributed in most parts of the country. [Cultivation] 1: Climate and soil, preferring mild and humid climate, tolerant of severe cold. To sunny, well-drained sandy loam is best, followed by clay loam and calcareous loam. 2: planting: a kind of seed propagation: spring sowing in Beijing in mid-April, fall sowing in late August. Mostly with strip sowing, open a shallow furrow, row spacing of 30 cm, the seeds will be evenly dispersed in the furrow, covered with thin soil. After sowing should often keep the soil moist, about more than 10 days seedlings. Second planting propagation, in the spring, when the old roots sprouted, the roots will be dug out and separated, each root with 1-2 young shoots, with digging and carrying, watering after planting. Three field management, after the emergence of seedlings often weeding, and loosening the soil 1-2 times, in the growing period can be chased with dilute manure 1-2 times, rainy season attention to drainage. [Collection] Picked in summer when the fruit spike is half withered, dried in the sun. [Herbs] The dried fruit spikes are long cylindrical or pagoda-shaped, 2-6 centimeters long, 1-1.5 centimeters in diameter, brown or light purple-brown. The persistent calyx is arranged in several to dozens of whorls, with 5-6 short-stalked persistent calyxes in each whorl, and 2 opposite bracts below. Bracts reniform, yellowish, longitudinal veins conspicuous, base cuneate, apex acuminate-caudate, abaxially white hirsute. Persistent calyx lip-shaped, upper lip broad, apex slightly 3-lobed, lower lip 2-lobed, lobes acutely triangular, outside with coarse hairs. Corolla and stamens deciduous. Inside the persistent calyx there are 4 nutlets, brown, shiny. The body is light and brittle, slightly fragrant, tasteless. Purple-brown color and large spikes are preferred. Mainly in Jiangsu, Anhui, Zhejiang, Henan, etc., also in other provinces. In Tibet, Yunnan, the flower and fruit spikes of Prunllahispida Benth. are also used in medicine. [The whole herb contains triterpenoid saponins, and its glucoside original is oleanolic acid, and also contains free oleanolic acid, ursolic acid, rutin, hyperoside, cis-caffeic aicd, trans-caffeic aicd, vitamin B1, vitamin C, vitamin K, huperzine, resin, and other substances, which can be used in the medicine. K, carotenoids, resins, bitters, tannins, volatile oils, alkaloids, water-soluble salts (about 3.5%, of which about 68% is potassium chloride), etc.. Flower spikes contain delphinidin and cornflower (Cyanidin) anthocyanosides, d-Camphor (d-Camphor), d-Fenchone, ursolic acid. [Pharmacology] 1: Antihypertensive effect, the aqueous, ethanol-water and 30% ethanol extracts of Xia Gu Cao have an antihypertensive effect on anesthetized animals. Decoction (100 mg/kg) injected into anesthetized dogs can produce significant and long-lasting antihypertensive effect, but is prone to produce rapid drug-resistant effect, such as to the dogs with skin bridges to serve Xia Ku Cao, 2 times a day, each time 2 grams / kg, can also make the blood pressure decreased, for renal hypertension dogs, after 2 weeks of continuous medication, the blood pressure has a medium degree of decline, and then return to the original level after discontinuation of the drug. The stem and leaves, spike and the whole grass of Xiaku Cao have antihypertensive effect, and the effect of spike is weaker. After cutting off the vagus nerve, the antihypertensive effect of Xia Gu Cao was obviously weakened. The excitation phenomenon was observed in the in situ and isolated rabbit heart and isolated toad heart, and it was believed that the hypotensive effect was not caused by the inhibition of the heart. When the dosage of total inorganic salts of Xia Ku Cao was comparable to that of decoction, there was no obvious antihypertensive effect, and when the dosage of Xia Ku Cao was more than double that of decoction, the degree of antihypertensive effect was only 1/4-1/6 of that of decoction, and when the dosage of Xia Ku Cao was given by gastric gavage, the antihypertensive effect appeared later but lasted for a long time, so it was thought that the antihypertensive effect of Xia Ku Cao was related to the inorganic salts contained in it. In recent years, some people have repeated the above test, and measured that the tincture (30% alcohol) of the stem and leaves of Xia Ku Cao contains potassium in a rather high amount, about 83 mEq/ml, and the content in the spike is less, and the oral intake of normal anesthetized dogs did not show obvious antihypertensive effect, and the decoction in which the inorganic salts are removed, and the antihypertensive effect is very little, i.e., Xia Ku Cao, injected intravenously, and its antihypertensive effect on the anesthetized animals, can not be ruled out in which inorganic salts (mainly potassium) factor, therefore, its antihypertensive effect is related to inorganic salts contained in it. The inorganic salt (mainly potassium) cannot be excluded from the hypotensive effect on anesthetized animals, so its hypotensive component and hypotensive principle need to be studied. 2:Antibacterial effect: According to the preliminary in vitro experiment, the decoction of Xia Gu Cao has inhibitory effect on dysentery bacillus, typhoid bacillus, Vibrio cholerae, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus, Streptococcus, and has a broader spectrum of antibacterial effect. Its water infusion (1:4) in the test tube also has inhibitory effect on some common pathogenic skin fungi. For experimental tuberculosis in mice, Xiaku Cao can reduce lung lesions. 3: Other effects: A decoction of Xia Ku Cao (1:50-1:200) caused tonic contractions in the isolated uterus of rabbits. In isolated rabbit intestines, high concentrations can enhance peristalsis. It has been reported that Xia Gu Cao decoction can inhibit the growth of S-160 tumor and Ehrlich ascites carcinoma in mice, but the mortality rate is higher than that of the group not given the drug, so it is actually its toxic effect. [Bitter, pungent, cold. 1: Bitter, pungent, cold. 2: "Bie Lu" non-toxic. 3: The Materia Medica has a slightly bitter, slightly pungent flavor. [It enters the liver and gallbladder meridians. 1: "Yunnan Materia Medica", enters the liver. 2: The Classic of the Materia Medica enters the foot syncopal and Shaoyang meridians. [Clearing the liver and dispersing knots. Treating scrofula, gall tumors, canker sores, nocturnal pain in the eyeballs, shyness and tears, dizziness, crooked mouth and eyes, musculoskeletal pain, pulmonary tuberculosis, acute jaundiced infectious hepatitis, hematochezia, and subluxation of the belt. 1: The Classic of the Materia Medica, main cold and fever, scrofula, rodent fistula, head sores, broken syndrome, dispersal of galls and knots, swollen feet and wet paralysis. 2: Supplements to the Diffractions of the Materia Medica (Supplements to the Diffractions of the Materia Medica), nourishing the blood. 3: "Yunnan Materia Medica" dispels liver wind and promotes meridians. It can cure crooked eyes and mouth, promote liver qi, open liver depression, stop musculoskeletal pain, eyeball pain, dispel scrofula and peripheral tuberculosis. 4: "Materia medica of raw herbs" (生草药性备要) removes phlegm and eliminates pus, treats scrofula, clears the upper part of the body and replenishes the lower part of the body, removes the membrane of the eye, and relieves pain. 5: "Materia Medica From New" (本草从新) treats scrofula, rodent fistula, gall tumors, firmness, carbuncle and breast rock. 6: "Science of Folk Herbs" has diuretic and bactericidal effect. Decoction can wash wounds and cure purulent exanthema. Wash the vagina, cure vaginal and uterine mucositis. 7: "Modern Practical Chinese Medicine" is a diuretic, effective in gonorrhea, uterine disease, and can cure hypertension, which can bring down blood pressure. [Usage and Dosage] For internal use: decoction of soup, 2-5 qian, boiled paste or into pills, bulk. For external use: decoction of water to wash or pound to apply. [Contraindications] Use with caution if the spleen and stomach are weak. 1: The Collected Notes of the Classic of Materia Medica (《本草經集注》), in which the earth melon is used as an enabler. 2: "The Essential Materia Medica", prohibited for those with Qi deficiency. [Recipe] 1: For scrofula saber, regardless of whether it has been ulcerated or not ulcerated, or has become a leakage for a long time: six taels of Xia Ku Cao. Two bells of water, decoction to seven points, remove the dregs, eat far from serving. If you are very weak, you should decoct a thick paste to serve. And apply to the affected area, more service is better. The regimen of all the wonderful formula" Xia Gu Cao Tang. 2: Treatment for the first stage of breast carbuncle: Xia Kucao, dandelion, each equal parts, wine decoction, or as a pill can also be. 3: treatment of liver deficiency eye pain, more than cold tears, tendon pain, and eye shyness and fear of the sun: Xia Gu Cao half two, one or two of the fragrant adenophora, *** for the finely ground, each serving one money, wax tea mix down, no time "Brief Jizhong Fang" to fill the liver scattered. 4: the treatment of hemorrhage more than: Xia Gu Cao for the end, each serving square inch dagger, rice drink mix down. Sheng Hui Fang 5: the treatment of red and white under the belt: Xia Gu Cao flowers, picked at the time of opening, dried for the end. Take two coins per serving and drink it with rice before eating. Compendium 6: Treatment of post-partum hemorrhagic dizziness: if the heart wants to die of gas, Xia Gu Cao is twisted into juice and served with one cup. Compendium" 7: the treatment of crooked eyes and mouth: Xia Kucao a money, gall star five points, windproof a money, hook hook vine a money. Decocted in water, point of water wine when lying down. Diannan Materia Medica 8: Treatment of dizziness and vertigo: Xia Kucao (fresh) three two, one or two Dong Mi. Stewed in boiling water. The East Fujian Materia Medica 9: treatment of epilepsy, hypertension: Xia Gu Cao (fresh) three two, one or two Dong Mi. Boiling water stewed service. Min Dong Materia Medica 10: prevention of measles: Xia Gu Cao five money to two. Water decoction, one dose a day, for three days. Xuzhou single prescription new medical method selection " 11: treatment of pediatric dysentery: one year old, Xia Gu Cao one or two, half a lotus five money, two to six years old, Xia Gu Cao, half a lotus each one or two, six to twelve years old, Xia Gu Cao, half a lotus each one or two and a half. Take with decoction of water. Selected Works. Infectious" 12: treatment of acute tonsillitis: sore throat, fresh Xia Gu Cao whole grass two to three taels, water decoction. Compendium of Herbal Medicine and Herbs Simple Checks and Prescriptions 13: treatment of pummeling injuries and gold sores: Xia Gu Cao pounded, compresses "health simple formula" [Clinical report] 1: treatment of tuberculosis: infiltration type, chronic fibrous cavity type, blood dissemination type of pulmonary tuberculosis, have a certain degree of efficacy. Take Xia Gu Cao 2 two, water decoction divided into 2-3 times oral, or with Xia Gu Cao 20 pounds of water decoction to 5,000 milliliters, plus brown sugar 2 city pounds of paste, morning and evening each served once, each 8-15 milliliters, 1 month for a course of treatment. After taking the medicine, cough, chest pain, hemoptysis, fever, sputum and other symptoms have disappeared or reduced, the lesions also have different degrees of absorption and improvement. For tuberculosis hemoptysis, can be used Xia Gu Cao one or two, to 2 two yellow wine with the right amount of water to soak, and then steamed to no smell of wine when filtered, adults 20-40 ml each time, 3-4 times a day, have the effect of stopping bleeding. 2:Treatment of exudative pleurisy: use one catty of Xia Gu Cao, add 2000 ml of water, decoct to 1000-1200 ml, each oral 30-50 ml, 3 times a day. If necessary with other symptomatic treatment. But do not add anti-TB drugs. Treatment of 9 cases of exudative pleurisy patients, except for 2 cases of improvement automatically discharged from the hospital, the rest are cured. Average hospitalization 35.6 days, fever 7.7 days, fluid absorption 24.7 days. 3: treatment of bacillary dysentery: take Xia Gu Cao 2 two, water immersion 10 hours, the fire decoction for about 2 hours, 4 times a day, 7 days for a course of treatment. Or take Xia Gu Cao dried flower spikes made of 100% fluid paste, 1-2 ml per child per year, 20-30 ml per adult, 2-3 times a day. After taking the medicine, the fever subsided in 3 days on average, the urgency and the number of stools disappeared or became normal in 4-6 days on average, and the disappearance of abdominal pain and mucous membrane lesions was slower, 10 days on average. No side effects were found during the medication period. 4: Treatment of acute jaundice infectious hepatitis: 75 cases of this disease were treated with Xia Gu Cao as the main treatment, of which 62 cases reached the clinical cure standard. Dosage and usage: daily use Xia Gu Cao 2 two, one or two jujube, add water 15000 ml, simmering decoction, pounding jujube for mud, decoction 300 ml, remove the dregs, 3 times to be served. In severe cases, the dosage can be increased. Or daily with Xia Gu Cao 2 two, lean meat 2 two (remove fat), each with 1200 ml of water, respectively, decocted for more than an hour, and then the two combined, simmering to 300 ml, remove the dregs, 3 times to be served. Generally 30 days for a course of treatment, if necessary, can be stopped 2-3 days after the second course of treatment. During the treatment period, vitamin B, C and a small amount of glucose can be given as adjuvant therapy. The disappearance or improvement of clinical symptoms of the patients ranged from 2 to 14 days, the regression of liver and spleen ranged from 10 to 65 days, jaundice ranged from 3 to 31 days, and the reversal of various flocculent turbidity tests ranged from 7 to 71 days, and no toxicity was found in the course of treatment. [Commentary] 1: Zhu Zhenheng: "The Materia Medica" says that Xia Gu Cao is a great cure for scrofula and disperses knotted gas. There is nourishing syncope yin blood, but does not say. Observe its retreat of cold and heat, false can be made, if the real one to line the scattered medicine with. External moxibustion, but also gradually take effect. 2: "Compendium": Lai Jushi "Yi Jian Fang" Xia Gu Cao treatment of eye pain, with sugar water soaked overnight, take it can relieve internal heat, slow liver fire. Building full good clouds, Xia Gu Cao treatment of eye pain to the night is very effective, or with bitter cold medicine point of the anti-worse, but also effective. Cover the eye even eye this, liver system, belonging to the syncopated yin meridian. Night even and point bitter cold medicine against very, night and cold also Yin reason. Xia Ku endowed with pure Yang gas, complementary syncopated yin blood, so the treatment of this such as God, to treat yin with Yang also. 3: "Materia Medica Tongxuan" Xia Ku Cao, tonic syncopated yin blood, and can dredge the knot gas. Eye pain, scrofula are all liver disease, so the construction of God's work. However, prolonged use also prevents injury to the stomach, with ginseng, art, peer, can be served for a long time without harm. 4: The Materia Medica Seeking Truth (本草求真)夏枯草, hard and slightly cold. According to the book on the treatment of work, more than that disperses the knot heat, can cure all the gall bladder wet paralysis, eye beads night pain and so on, it seems to be cold to clear the heat of the meaning of carry on. Why book and say gas endowed with pure Yang, and complementary liver and blood, no self-contradiction? How do you know that although the gas is cold and flavor is Xin, where the knot Xin is scattered, although the gas is cold is warm, so the cloud can be used to replenish blood also. Therefore, all the heat and liver meridians and other diseases, this treatment is not effective, in order to obtain the dissolution of the work of the book ear. If the internal fire, the treatment should not be used. 5: "Chongqing Hall Essentials": Xiaku Cao, slightly pungent and sweet, so the scattered knot, both and yang and yin function, blood loss after sleeplessness is served when sleep, the nature of the visible carry-over. The flavor is especially sweet when it is aged for a long time, and it is superior in medicine. 6: "Justice of the Materia Medica": the nature of Xia Kucao, "Ben Jing" of the bitter Xin, and there is no cold word, Sun's ask the Hall of Scripture this can be proved. And since the "thousand jin" later, all add a cold word in the word under the word Xin, but this grass from the summer solstice wither, so get this name. Danxi said that its endowment of pure Yang gas, get Yin gas and that is to die, the view of its main scrofula, break the knot, swollen feet paralysis, are to XuanTong diarrhea and chemical long, must have a mild gas, can be eliminated to release the firm condensation, dredge the room stagnation, not the role of the cold. Shi Niao "Feng Yuan" changed to bitter Xin Wen, its own rationale, bitter can diarrhea, Xin can be sparse, warm can flow, good at cathartic liver and gallbladder wood fire of the stagnation, and smooth the operation of qi and blood. Any condensed phlegm and gas, wind and cold paralysis, are its specialty. /aa12.html