Extended data
1. Capsules refer to solid preparations made by filling drugs into hollow hard capsules or sealing them in elastic soft capsules. The hollow hard capsule shell or elastic soft capsule shell is made of gelatin, glycerin, water and other medicinal materials, but the preparation methods are different with different proportions of each component. Gelatin capsules are the most popular two-part capsules in the world. The capsule consists of two parts of capsule shell. Capsules come in various sizes, including 000# and 00# capsules. Capsules can also be colored and printed to show a unique customized appearance. The capsule body part has a tapered edge, which can successfully package the capsule on a high-speed filling machine. Double locking ring system can make capsules pre-locked before filling and completely nested together after filling drugs. The design of the capsule also includes air holes to avoid unnecessary air pressure in the capsule during high-speed filling and rebound.
Second, there is nothing wrong with cold water capsules. On the contrary, taking medicine in hot water may bring some disadvantages. Many times, drugs are put into capsules to cover up the bad taste of drugs, and if you eat capsules with too hot water, the capsules will be destroyed in advance and the taste will be poor. Moreover, in hot water, the capsule will become soft and sticky, and if you don't drink enough water, it may stick to the esophagus. Moreover, if it is an enteric-coated capsule, hot water may destroy the anti-gastric function of the capsule, so that the drug that should be protected cannot reach the intestine smoothly through the stomach. When taking capsules, you can take them with cold water or warm water. Pay more attention to water quantity than water temperature. Many people only take a sip of water when taking medicine, or simply dry their throat, but in fact, they should drink more water to ensure that the medicine can reach the stomach smoothly, and it can also reduce the irritation of some drugs to the esophagus. Therefore, taking capsules with cold water will not affect the dissolution of capsules and the absorption of drugs.