2. mussels will have bacteria if they are not cooked well. The main bacteria in mussels is Vibrio parahaemolyticus, which has strong heat resistance and can only be killed when it is above 80 degrees Celsius. In addition to the bacteria brought by water, there can also be parasitic eggs, bacteria and virus pollution brought by seafood processing. Generally, boiling water can be completely disinfected in 4 to 5 minutes. After that, it takes fifteen to twenty minutes to cook the mussels.