Gout disease is caused by what, how to prevent
Suggestion: Gout is congenital genes (constitution) and acquired dietary environment two factors **** with the cause, if no genetic gout constitution (not necessarily have a family history of gout), it is not easy to eat and drink too much and cause gout, but if you have a high uric acid constitution, can be controlled through the diet to reduce or prevent the onset of gout. Knowing that uric acid is too high, the first thing to do is to find out the causes of uric acid elevation, rather than blindly using medication, in order to formulate the correct direction of treatment. For example, obesity, drugs (such as aspirin, anti-tuberculosis drugs, diuretics, etc.), blood disorders, tumors, or renal efficacy of the need for medication, specific rheumatologist for advice. Genetic factors of gout: gout patients may have a family genetic history, or call it a tendency to develop in the family, but in generations and family lines, gout appears irregular. In patients with primary gout, about 10-25% of those with gout have a family history of gout, with a range of 8-30% reported by country. Hyperuricemia is present in 15-25% of close relatives of gout patients. Primary gout is inherited in an autosomal dominant manner, but the epistasis is incomplete. A number of factors can influence the genetic expression of gout, such as age, sex, diet and renal function. Two inborn abnormalities of purine metabolism have been identified as sex-linked inheritances , see the Enzyme Metabolism Defects section of the Gout Classification. Glycogen accumulation disease type I (von Gierke's disease) in secondary gout is autosomal recessive. The genetic profile of hyperuricemia is highly variable and may be polygenic.