It is best to have an interval of more than 2 hours, but it is generally not recommended to eat together, especially for people with poor gastrointestinal function. It is best to have a longer interval. Persimmon contains a lot of tannic acid, which will combine with protein in crab, and then cause nausea, vomiting, stomachache and other symptoms, especially for people with cold stomach, so people with poor gastrointestinal function had better not eat these two foods together.