If you don't take the train, you can transfer in Wuhan, but the time is not good, and the waiting time for transferring in the middle is too long. It would be easier to take the direct train.

Train number, origin station, terminal station, vehicle type, departure station, departure time, arrival station, arrival time, mileage, duration, second class seat

D3077 Nanjing Nanyichang East EMU combined fertilizer 08:37 Jingzhou 12:46 568 04:09 167

D3072/D3073 Shanghai Hongqiao Yichang East EMU combined fertilizer 10:16 Jingzhou 14:22 568 04:06 167

D3081 Nanjing Nanjing Yichang East EMU combined fertilizer 16:24 Jingzhou 20:30 568 04:06 167

D3006/D3007 Shanghai Hongqiao Yichang East EMU combined fertilizer 17:14 Jingzhou 21:00 568 03:46 167

For ordinary trains, first take a train in Hefei to Hankou, and then transfer to a train in Hankou to Jingzhou.

Train number, origin station, terminal station, vehicle type, departure station, departure time, arrival station, arrival time, mileage, duration, hard seat,

K722/K723 Nanjing Chengdu East Air-conditioned Express Hefei 10:46 Hankou 15:25 364 04:39 54

T250/T251 Wuhan Chengdu East Air-conditioned Express Hankou 20:16 Jingzhou 22:28 204 02:12 33

The total fare is 87, which is quite cheap, but the waiting time is just long enough for a train trip.