There is no direct bus from East Street to Nanhu Station. You can walk a few steps. Take bus 58 to Shunhe Street or Hongxinglou and you can go directly to Nanhu Station. There is no direct bus from Nanhu Station to Shuangbei Middle Street, but you can take bus 40.

Or take bus 10 to the train station and then transfer to bus 39 to get to Shuangbei Middle Street.