Wart is a kind of skin surface vegetation caused by human papillomavirus. The incubation period is 1 ~ 3 months, and it can spread by itself. The virus exists in spinous cells, which can promote cell proliferation and form verrucous damage. According to clinical manifestations and locations, it can be divided into common warts, flat warts, plantar warts, genital warts (condyloma acuminatum), oral warts, throat warts and verrucous epidermal dysplasia. Warts are caused by human papillomavirus infection. It can be transmitted through direct or indirect contact, and perianal and genital warts are mostly transmitted through sexual contact. Trauma or skin injury is an important factor of human papillomavirus infection. The course of wart has an important relationship with the immune system, and the incidence of wart increases in patients with low immune function, such as kidney transplantation, malignant lymphoma, chronic lymphocytic leukemia and lupus erythematosus. However, the mechanism of long-term existence of warts in relatively healthy people is still unclear.
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