Can colon cancer be cured? First, it is related to staging. Most early colon cancer can be cured by surgery, and the cure rate is very high. Mid-stage colon cancer, if accepted standard radical surgery, most of them can be cured. But some of them will have recurrence and metastasis. In the advanced stage of colon cancer, the cure rate can be almost zero, and it is generally incurable. Second, whether colon cancer can be cured is also related to the choice of surgery and whether standard radical surgery can be performed. If we can cooperate with the standard radical surgery, we have more hope to achieve radical cure. Standardized comprehensive treatment after radical surgery, standardized chemotherapy and follow-up observation are very important for the treatment of rectal cancer.