1. Individual patients in the beginning of the drug temporary bloating, nausea and other gastrointestinal reactions, continue to use the drug disappeared on their own.2. A small number of patients may appear rash, allergic asthma, anaphylactic shock, fever and other allergic reactions, a very small number of patients appear hemolytic reaction, once the above adverse reactions, the drug should be discontinued and symptomatic treatment.3. Occasionally acute intravascular hemolysis: chills, fever, jaundice, waist pain, deepening of urine color, etc.. , lumbago, deepening of urine color, etc.