How to replenish estrogen after menopause is the current medical research hotspot, in which transdermal estradiol supplementation of estrogen is the future trend. According to the research, most of the physical and mental troubles after menopausal extinction of women are caused by the lack of estradiol. The earlier popular oral estrogen will have certain side effects due to the action of stomach acid, intestinal microorganisms and liver, and the supplemented in is not the estradiol that the body lacks and really needs, but the estrone that the body does not need.

And direct transdermal supplementation of good estrogen preparations estradiol gel, ointment (such as YiTaiLi - benzoic acid estradiol ointment), etc., because it does not need to go through the stomach, intestines and liver, will not be destroyed by gastric acid, intestinal microorganisms and liver, etc., direct supplementation of the body's own need for their own natural estradiol, so there will be no side effects of estrone. Studies have found that estradiol is an intracellular receptor hormone, freely moving in and out of cells, and is very easily absorbed transdermally, making it the easiest of all drugs to be absorbed through the skin. That is why transdermal supplementation with estradiol gel after extinction, estradiol benzoate ointment, etc. are more efficient at boosting estradiol in the blood and making estrogen supplementation more effective. Today, 70% of women supplementing estrogen in the United States already use transdermal estradiol gels, creams or patches to supplement estradiol.