Simply put, leukemia is an overproduction of blood cells, and aplastic anemia is an abnormality of bone marrow hematopoiesis Leukemia: a progressive malignant disease occurring in hematopoietic organs and characterized by abnormal proliferation and development of white blood cells and their precursor cells in the blood and bone marrow. It is a class of clonal malignant diseases with abnormal hematopoietic stem cells. The leukemic cells in its clones lose the ability to further differentiate and mature and stagnate at different stages of cell development. Leukemia cells proliferate and accumulate in the bone marrow and other hematopoietic tissues and infiltrate other organs and tissues, while normal hematopoiesis is inhibited, resulting in clinical manifestations of anemia, hemorrhage, infections, and infiltration of various organs. Aplastic anemia: bone marrow hematopoietic stem cells and/or hematopoietic microenvironment damage blood disease. It is a bone marrow hematopoietic failure disorder, mainly manifested by low bone marrow hematopoietic function, total blood cell reduction and anemia, bleeding and infection symptoms. It may be due to: (1) multiple causes of hematopoietic stem cell or stromal cell injury; (2) abnormal production or function of hematopoietic regulatory factors; (3) enhanced expression of death receptors on the surface of hematopoietic stem cells or increased sensitivity to apoptosis; (4) the body produces abnormal autoimmunity against hematopoietic stem cells.

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