The incidence of lymphadenopathy in the initial symptoms of AIDS is 55%- 100%. When patients in high-risk groups have systemic lymphadenopathy that cannot be explained by other reasons, they are probably infected with HIV.

Lymphadenopathy can occur all over the body, but it is more common in cervical, supraclavicular, submandibular or axillary lymph nodes. The swollen lymph nodes are not fused, hard, occasionally tender, and the surface skin has no change.

AIDS patients in the late stage, swollen lymph nodes with bacterial infection, can appear red, swollen, hot pain symptoms; Especially when the CD4+T lymphocyte count is lower than 200, the patient will have fever for a long time, accompanied by one or more lymph nodes in the neck. Even if there is no tuberculosis focus in the lungs, we should attach great importance to the possibility of tuberculosis in lymph nodes.

Generally speaking, the degree of lymphadenopathy is related to the titer of HIV antibody in serum. In addition, AIDS is accompanied by lymphoma, including Burkitts' lymphoma, immunoblastic lymphoma and Hodgkin's disease, and lymphadenopathy may also occur.