1) laxative effect: the osmotic pressure formed in the intestine is not absorbed by oral administration, which keeps a large amount of water in the intestine, expands the intestine, stimulates intestinal peristalsis, and makes the contents of the small intestine quickly enter the large intestine and discharge watery stool. Clinically, it is mainly used to eliminate toxins in the intestine, and also used for catharsis of some anthelmintics. However, it should be noted that if the magnesium sulfate aqueous solution is too concentrated, the defecation time will be slow (the defecation time will be longer when taking 20% magnesium sulfate 100ml, and the defecation time will be about 2 ~ 4 hours when taking 5% solution containing the same amount of magnesium sulfate), so it is necessary to drink more water at the same time when taking magnesium sulfate for catharsis. If you want to excrete too much water from your body, it is better to use concentrated solution. Usage: Take 5 ~ 20g orally each time, usually take 100 ~ 400ml water on an empty stomach in the morning, or take it after dissolving it in water.
2) Choledocholithiasis: Oral high-concentration (33%) magnesium sulfate solution or catheter injected directly into duodenum can stimulate duodenal mucosa, reflexively cause relaxation of common bile duct sphincter and contraction of gallbladder, promote gallbladder emptying and produce choledocholithiasis. Clinically used for obstructive jaundice and chronic cholecystitis. Usage: 2 ~ 5g each time, three times a day, before or between meals. You can also take 33% solution, each time 10ml.
3) Effect on central nervous system: After injection of this product, the concentration of magnesium ions in extracellular fluid can inhibit the central nervous system, reduce the release of acetylcholine from motor nerve endings, and block the peripheral neuromuscular junction, thus having the functions of sedation, spasmolysis, relaxation of skeletal muscle and reduction of intracranial pressure. Clinically, it is used to treat convulsion, eclampsia, uremia, tetanus, hypertensive encephalopathy and acute renal hypertensive crisis. Usage: intramuscular injection of 25% solution, 4 ~10 ml each time; Or use 5 ~ 10% glucose injection to dilute the 25% solution of 10ml to the concentration of 1% or 5%, and then drip intravenously.
4) Effect on cardiovascular system: Injecting excessive magnesium ions can directly relax the smooth muscle of peripheral blood vessels, causing obstacles in the transmission of sympathetic ganglion impulses, thereby dilating blood vessels and lowering blood pressure. Clinically, it is better for patients with frequent angina pectoris and ineffective other treatments, especially for patients with hypertension. Usage: In the treatment of angina pectoris, 5% ~ 10% glucose injection 10ml dilution 10% solution 10ml can be used, and then slowly intravenous injection, once a day, for 1 0 days.
5) Anti-inflammatory and detumescence: 50% solution of this product is externally applied to the affected area, which has anti-inflammatory and detumescence effects.