Clinically, it is often used for bleeding diseases such as pulmonary and gastrointestinal bleeding, hematuria and metrorrhagia. It can also be used for traumatic bleeding, and can be used to grind and spread the affected area. Cuttlefish bone is also used for leucorrhea, nocturnal emission and other diseases. Cuttlefish bone can also be used for treating sores with multiple pus and long-term unhealed sores, and can be grinded into powder for external application. For those with damp-heat fire toxin, it can be used equally with Cortex Phellodendri and Indigo Naturalis. Cuttlefish bone is also used for the pain of ulcer, pantothenic acid or stomach bleeding. In addition, cuttlefish bone is also used to cause diseases and lumps.