When pregnant women are found to be deficient in G-6-PD, there is a14 chance for their sons and a14 chance for their daughters to inherit this gene, but they don't necessarily get sick. If the husband is found to be deficient in G-6-PD, the son will not inherit this gene, and the daughter will have a chance of 1/2 to inherit this gene, but it is not necessary to get sick. If both husband and wife are G-6-PD deficient, among the daughters born to them, the son and daughter each have a 1/4 chance to inherit the disease, and the daughter has another 1/4 chance to inherit the gene, but it is not necessary to get sick.
Common preventive measures are: where both or one of the pregnant women and her husband is suffering from silkworm bean disease, the pregnant women should start taking phenobarbital after 28 weeks of pregnancy, with a dose of 0.03-0.06 per night until delivery, which should not be less than 3 weeks. Pregnant women with anemia should be given iron and vitamin E. Try to avoid fetal distress, asphyxia and delivery trauma during delivery. If the asphyxia is severe, monitor blood sugar and inject glucose intravenously in time, and leave cord blood for blood type, bilirubin and G-6-PD determination. Check the red blood cells, hemoglobin, nucleated red blood cells and reticulocytes on the first day after delivery, and give phenobarbital 5mg/kg, 3 times a day for 5 days. If hemolysis occurs quickly, give corresponding treatment, avoid infection and use drugs that are easy to induce hyperbilirubinemia, and ban breastfeeding for 2 weeks.