Category: Medical Health

Problem Description:

Because I have chronic cetirizine, I only need to take one cetirizine hydrochloride plus two pills when I get sick. I'll be fine after taking vitamin C Yinqiao tablets. I've taken about 10 boxes since I got sick, totaling 70 to 80 tablets. I wonder what the consequences will be if I continue to eat like this? If anyone knows, please help me answer it, thank you! ! !

Analysis:

Drug name

Generic name: Cetirizine Hydrochloride Tablets

Previous name:

Trade name:

English name: Cetirizine Hydrochloride Tablets

Chinese Pinyin: Yansuanxitiliqing Pian

The main ingredient of this product is cetirizine hydrochloride, its chemical The name is (±)-2-[2-[4-[(4-chlorophenyl)benzyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride

The structural formula is:

Properties

This product is white or off-white tablets

Pharmacology and Toxicology

This product is a selective histamine H1 receptor antagonist. Animal experiments show that this product has no obvious anticholinergic and anti-5-hydroxytryptamine effects. It cannot easily pass through the blood-cerebrospinal fluid barrier and act on central H1 receptors. When used clinically, the central inhibitory effect is mild

Pharmacokinetics

According to reports, it is absorbed from the gastrointestinal tract after oral administration. When healthy adults take 10 mg of cetirizine orally once, the time to reach peak plasma concentration (tmax) is 30 to 60 minutes. The peak plasma concentration is 300ng/ml. The binding rate of cetirizine to plasma proteins is high. The plasma half-life is about 10 hours. About 70% of the drug is excreted in the urine as unchanged drug, and a small amount is excreted in the feces

Indications

For seasonal or perennial allergic rhinitis, urticaria and skin itching caused by allergens

Usage and dosage

Oral: Adults or over 12 years old For children, take 10 mg once a day, or as directed by your doctor. If adverse reactions occur, it can be changed to 5 mg in the morning and evening. For children aged 6 to 11 years old, the recommended starting dose is 5 mg or 10 mg, once a day, depending on the severity of symptoms. For children aged 2 to 5 years old, the recommended starting dose is 2.5 mg once a day; the maximum dose can be increased to 5 mg once a day, or 2.5 mg once every 12 hours

Adverse reactions

Adverse reactions are mild and transient, including drowsiness, somnolence, headache, dizziness, agitation, dry mouth and gastrointestinal discomfort. Occasionally, aspartate aminotransferase is slightly elevated

Contraindications

Contraindicated for those allergic to this product

Precautions

1. The dosage should be halved in patients with renal impairment

2. Avoid use after drinking alcohol

3. Use with caution by drivers, operators of machines or people working at heights

Use by pregnant and lactating women

Pregnancy Contraindicated for pregnant and lactating women

Medication for children

Medication for elderly patients

Drug interactions

No interactions with other drugs have been found reported, but caution should be exercised when taking sedatives at the same time

Drug Overdose

This drug has no specific antagonist. Patients with severe overdose should have gastric lavage immediately, use supportive therapy, and maintain strict long-term Observe changes in condition

Specifications

10mg

Storage

Keep in a dark and sealed container

The main side effects of this medicine are: It is drowsiness, and other side effects are rare and can be taken for a longer period of time.