1. Anemia means that the hemoglobin concentration, red blood cell count and/or hematocrit per unit volume in peripheral blood are lower than the normal standards of the same age, sex and region. It is often accompanied by other nonspecific symptoms and signs, such as fatigue, inattention, pale conjunctival nails, etc. Anemia can be divided into small cell anemia, large cell anemia and normal cell anemia according to the mean volume of red blood cells (MCV). Among them, iron deficiency anemia (small cell hypopigmentation) is the most common anemia, which is more common in women of childbearing age.
Diagnostic criteria female: hemoglobin (HB)
Effect on pregnancy: During normal pregnancy, the female plasma volume increases more than red blood cells, resulting in hemodilution. If anemia before pregnancy is not corrected, it will lead to aggravated pregnancy symptoms, and anemia has a great impact on pregnant women and fetuses.
Risk classification (1) Extremely severe anemia: red blood cells
Prenatal eugenics consultation (1) Moderate anemia (HB
2. Idiopathic thrombocytopenic purpura Idiopathic thrombocytopenic purpura (ITP) is a clinical syndrome with increased platelet destruction due to immune mechanism. It is the most common type of thrombocytopenic purpura, characterized by peripheral thrombocytopenia, shortened platelet life, normal or increased megakaryocytes in bone marrow, and accelerated platelet renewal. Chronic ITP is common in 20-50 years old, mostly in women, and can be manifested as bleeding, anemia and so on.
Diagnostic criteria The main diagnostic criteria of this disease should be repeated laboratory tests according to bleeding symptoms, such as thrombocytopenia, prolonged bleeding time, enlarged or slightly enlarged spleen, increased or normal megakaryocytes in bone marrow, accompanied by maturation disorder and increased anti-platelet antibodies, and secondary thrombocytopenia should be ruled out.
Risk classification: pregnancy after remission, and close monitoring during pregnancy. The risk is level C. ..
Pre-pregnancy eugenics guidance suggests that all patients with thrombocytopenia should go to a specialist before pregnancy, because pregnancy may lead to aggravation. Patients with severe thrombocytopenia or unresponsiveness should avoid pregnancy. Platelet number
Leukemia Leukemia is a clonal malignant disease with abnormal hematopoietic stem cells. The leukemia cells in its clone lost the ability of further differentiation and maturation, and stagnated at different stages of cell development. Leukemia cells proliferate and accumulate in hematopoietic tissues such as bone marrow and infiltrate other organs and tissues, while inhibiting normal hematopoiesis. The clinical manifestations are anemia, hemorrhage, infection and infiltration of various organs.
Diagnostic criteria The diagnosis of this disease should be based on symptoms and signs such as fever, hemorrhage, anemia and leukemia cell infiltration, combined with blood cell count and classification, bone marrow examination, immunophenotype and molecular biological detection.
Influence on Pregnancy Leukemia has a great influence on pregnant women and fetuses.
The risk classification is not suitable for pregnancy, and the risk is X.
Prepregnancy eugenics guidance suggests that it is not suitable for pregnancy.