Mulberry skin was twisted into a grooved tube, and the remaining cork was yellow-brown.
Tough longitudinal crack exposes fibers, clearing lung, relieving asthma and eliminating edema.
[Source] Shennong Herbal Classic.
[Original] This product is the root bark of Mulberry, a dicotyledonous plant of Moraceae.
[Origin] It is produced in most parts of the country.
[Harvest] Mining in winter. Wash, scrape off the yellow rough skin on the surface, cut the skin longitudinally, tap with a wooden hammer to separate the skin from the main part, peel it off and dry it in the sun.
[Medicinal material shape] It is long and twisted plate-shaped, cylindrical or slotted at both sides, with different length and width, and the thickness is 0.1-0.5cm.. The outer surface is yellowish white, with a small amount of brown or reddish brown spots (residual cork), and the inner surface is yellowish white or grayish yellow, smooth, with thin longitudinal stripes, and some longitudinal cracks expose fibers. The green body is light and tough, not easy to break, easy to tear longitudinally, and white dust flies out when tearing, which is slightly fragrant and sweet.
It is best to be white in color, thick in skin and full of powder.
[Processing] Scrape the rough skin of the original medicinal materials, wash, slightly stuffy, shred and dry in the sun.
Stir-fry the mulberry bark, shred the mulberry bark, mix it with refined honey (100 kg of mulberry bark, refined honey 25 kg, diluted with appropriate amount of boiling water), slightly stuffy, stir-fry with slow fire until golden brown and not sticky, take it out and let it cool. After honey baking, the nature of cold diarrhea is alleviated, and the effect of moistening lung and relieving cough is enhanced.
【 Ingredients 】 Contains umbelliferone, scopoletin and flavonoids, such as morin, mulberry rope, morin, cyclic morin, cyclic morin, etc.
【 Sexual taste and meridian tropism 】 It is sweet and cold, and enters the lung meridian.
【 Function 】 Clearing lung, relieving asthma, diuresis and detumescence. Used for cough and asthma due to lung heat, facial edema and dysuria.
【 Prescription Name 】 Cortex Mori, Cortex Mori and Radix Mori are baked with honey.
[Usage and dosage] Decoct, 5~ 15g. It is appropriate to use purging lung and promoting diuresis, calming liver and clearing fire; Cough due to lung deficiency should be roasted with honey.
[Storage] Store in a ventilated and dry place, and store the baked products in a sealed way.
Press: 1. The roots of China mulberry and chicken mulberry are also used as medicine in many places.
2. In some areas, the root bark of Broussonetia papyrifera fell off. And zheshu. It is worth paying attention to the mixture of mulberry bark belonging to the same family as medicine. Both of them are similar in appearance to mulberry bark, but the subcutaneous part of Broussonetia papyrifera root is slightly bifurcated, with white outer surface, yellow-brown cork residue and punctate lateral root marks. It is easy to tear longitudinally when it is broken, and it has a slight odor. The outer surface of Broussonetia papyrifera root bark is rough, grayish white, with orange cork residues, lateral wrinkles and granular protrusions, and occasionally lateral root marks and perforations. Longitudinal tears often break halfway, with a slight beany smell and bitterness.
Main ingredients: umbelliferone, scopoletin, flavonoids, mulberry bark, mulberry, cyclosporine, cyclosporine, etc.
Description: It is a long and twisted plate, tubular or grooved on both sides, with different lengths and widths and a thickness of 0.1-0.5cm.. The outer surface is yellowish white, with a small amount of brown or reddish brown spots (residual cork), and the inner surface is yellowish white or grayish yellow, smooth, with thin longitudinal stripes, and some longitudinal cracks expose fibers. The green body is light and tough, not easy to break, easy to tear longitudinally, and white dust flies out when tearing, which is slightly fragrant and sweet.
Various exhibitions
1. Gaoli: Mulberry bark, willing to tonify the deficiency with the deficiency of consolidating the roots and relieve cough with the essence of purging the lungs. Mulberry bark is natural and impure, and should not be used more.
2. "Outline": Mulberry bark is good at benefiting small water and actually purging its son, so it is suitable for those with water vapor in the lungs and lung fire. Ten doses of cloud, dry to remove moisture, mulberry bark, red beans for the genus. Qian Yi, a doctor in Song Dynasty, used white powder to treat lung heat hyperactivity, wheezing after coughing, swollen face and body heat, and diarrhea. Mulberry bark and wolfberry bark can purge fire from childhood, licorice can purge fire and slow down the middle, and japonica rice can clear lung and nourish blood, which is the criterion of purging lung. Tianyi Luo, a doctor of Yuan Dynasty, said that purging lung and latent fire should supplement healthy qi, and purging evil spirits should be right. If the lung deficiency is small and easy to see, don't use it.
3. "Drug meaning": Mulberry bark, which dissipates heat, is mainly used to relieve asthma and cough, and phlegm and blood stasis are intertwined, all of which are depressed by pathogenic factors, and the lung orifices are not smooth, so as to disperse the infiltration and benefit the lung qi, and the syndromes are self-healing. Therefore, it is necessary to clear the lungs. This can be used to treat water vapor edema outside the intradermal membrane, skin pathogenic heat, wind drift, dryness and itching, and can be removed. When used together with chamomile and lentils, it can relieve nasal congestion and heat depression, and when used together with Radix Adenophorae and Radix Astragali, it has the effects of stopping red intestine and stopping bleeding.
Mulberry bark is also called mulberry root bark in classics, and mulberry root bark and mulberry bark in Huangmeng, which is the dry root bark of mulberry. Mulberry leaves fall before germination in late autumn and the following spring, and the roots are dug, the yellow-brown rough skin is scraped off, the mulberry leaves are cut vertically, the roots are peeled off, and the human medicine is dried. Mulberry bark is cold and sweet, and enters the lung meridian. It has the effects of dispersing lung qi, relieving asthma, promoting diuresis and reducing swelling. Mulberry bark is widely used.
pharmacological action
1, pharmacological action of cortex mori, and medicinal use of cortex mori have been recorded in ancient books. "Bielu" contains: "Removing lung moisture, vomiting blood, heat thirst, edema, fullness in the stomach, benefiting waterways, and sewing golden sores". "herbal hook yuan" contains: "live on water, cough or stir-fry with honey." Compendium of Materia Medica says: "If you are afraid of diarrhea, stir-fry it with honey." Depei Materia Medica: "Evacuate wind and heat, use raw materials, stir-fry with honey and water". "Materia Medica" records: "Mulberry juice can cure children's aphtha. When it is applied, it will be dry and painful, even if the mulberry skin is peeled off, the juice can enter the sore."
The specific pharmacological effects of Cortex Mori are as follows:
Hypoglycemic effect 1. 1 After Moraine was isolated from mulberry bark in 1970s and proved to have hypoglycemic effect, Moran A, a hypoglycemic substance, was isolated from mulberry bark. It is a glycoprotein with a molecular weight of about 7.5x 10', and the protein part accounts for 57.4%. Experiments confirmed that Moran A had a dose-dependent hypoglycemic effect on alloxan-induced hyperglycemia mice. If the relative blood sugar level of hyperglycemia group is 100%, lnor is given respectively. After 7 hours, the blood glucose levels of lnA3, 10 and 30m/kg decreased to 6 1%, 38% and 34% respectively, and after 24 hours, they were 77%, 66% and 49% respectively. Teng Deyi and others found that the large (30 red kg) and medium (15g/kg) dose groups of compound mulberry bark concentrated solution had obvious hypoglycemic effect on alloxan-induced diabetes in mice, and had certain hypoglycemic effect on glucose hyperglycemia.
Diuretic effect of 1.2 Zuo Yan et al. studied the effects of oral mulberry bark decoction in rabbits and oral or intraperitoneal injection of mulberry bark water extract or n-butanol extract in rats. They all have diuretic effect, and the urine volume and excretion of sodium, clock ions and chloride increase. Sun Jingyun and others believe that scopoletin is an effective component of diuresis in mulberry bark. Zhang Wenjuan and others compared the diuretic effect and toxicity before and after bark removal. The results showed that 8.4/kg mulberry bark with or without coarse skin could significantly increase the urine volume of rabbits, but had no obvious effect on the diuretic effect of mulberry bark before and after coarse skin removal, and its toxicity was greater than that of mulberry bark without coarse skin removal.
1.3 Anti-human HIV [HWl] in vitro experiments showed that HIV, the pathogen of AIDS, attached to CD4 cell receptors of T helper cells through outer membrane glycoprotein (gp 120), and the cells fused to form syncytial initiation infection ring. 1- deoxynojirimycin, the effective component of Mulberry Bark, is an inhibitor of O- glucosaminidase, which can interfere with the synthesis of polysaccharide structure in one side chain of gpl2ON, thus blocking the combination of gp2O and CD4, reducing or preventing the formation of syncytium and weakening the infectivity of HIV. In vitro experiments also proved that when the 2.Ommol/L. of 1- deoxynojirimycin dropped below 10, the infectivity of HIV to C8 166 cell line could be changed by 10. Luo Shide and others think that the flavonoids momrusin, kuwanon H and Morus in 4- glucoside in mulberry bark also have certain anti-HlV activity.
Hypotensive effect 1.4 1983, Japanese Fufu used mulberry bark extract for the first time to reduce blood pressure in rabbits. Subsequently, Nomura and others pointed out that. The antihypertensive components of Cortex Mori include Kuwanong, H, Sanggennong C and D, and Mulberry Furan C, F and G, and the antihypertensive mechanism of these components may be related to the inhibition of cAMP phosphodiesterase activity. 1995, Sato et al. in Japan used essential hypertensive rats to freely eat the feed mixed with mulberry leaves 12- 18 weeks, and it was also found that it could reduce diastolic blood pressure.
1.5 antibacterial activity of sanguson AuwanonC, j, l and sanguson a, b, c, d have antibacterial activity against staphylococcus aureus and Bacillus subtilis, kuwanon J, l and sanguson a, b, c have antibacterial activity against streptococcus and sanguson, and kuwanon C, l, a have antibacterial activity against mycobacterium smegmatis. Morigenin, kuwanonC and sa 8 genonA, c have no effect or only weak activity on gram-negative bacteria and fungi (except rice pear spores).
2 Development and utilization of mulberry bark
2. 1 medicinal mulberry bark 100g, ginger 10g, detention period 1t, Huang Wu 1t, Polygonum multiflorum Thunb 109, Zanthoxylum bungeanum 10g, 75. Compound mulberry bark has a good effect on treating male alopecia and has no side effects. Jujube and mulberry bark soup consists of mulberry bark 9g, Alisma orientalis 1 0g, Scrophularia12g, Ophiopogon japonicus10g, Lycium barbarum bark 9g, Huang Fen 9g, Inula flower 6g, Glycyrrhiza uralensis 6g, Chrysanthemum 6g and Platycodon grandiflorum 6g per day. Mulberry bark soup consists of Mulberry bark, Fritillaria, Almond, Coptidis Rhizoma, Perilla frutescens, Pinellia ternata, Scutellariae Radix and Dioscorea zingiberensis. It can be used for treating common cold, acute and chronic bronchitis, bronchopneumonia, bronchial asthma, and even chest obstruction and hemoptysis. Mulberry bark L is prepared from mulberry bark, Huang Fen, Sophora flavescens and Gardenia each 65,438+/-00g, Flos Lonicerae and Herba Artemisiae Scopariae each 65,438+-05g, Herba Hedyotidis Diffusae 25g and Glycyrrhrizae Radix 5, and mixed with external inverted lotion (sulfur and rhubarb each 65,438+-00g), ground into fine powder, and added with1.
2.2 make mulberry root bark, soak in hot water, filter and concentrate to obtain powder I; Boiling decomposed mulberry root bark, extracting with ethanol, filtering, and concentrating into powder. L and were mixed to obtain an antihypertensive agent.
2.3 Preparation of Mulberry Root Wine The mulberry root is air-dried, chopped and boiled to obtain a soaking solution, then a proper amount of shochu is added to the residue for cooking, and the cooking residue is soaked in the soaking solution, and finally edible alcohol and a proper amount of essence are added to the soaking solution to obtain Mulberry Root Wine.
2.4 Prepare mulberry roots of conditioner, boil, cool, add ethanol, filter, and add proper amount of essence to the filtrate to obtain conditioner.