Water, electrolyte disorders: water, electrolyte disorders due to side effects are more common, manifested as dry mouth, thirst, muscle cramps, nausea, vomiting and extreme fatigue and weakness. Including: susceptible to hypokalemia (related to the potassium excretion effect of hydrochlorothiazide), such as long-term potassium deficiency can damage the renal tubules, severe potassium loss can cause vacuolar changes in the renal tubular epithelium as well as severe tachyarrhythmias
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