Yes. Take a sip of durian and a sip of wine. Don’t think that this is a great experience. If you are not careful, you may lose your life. Durian mixed with wine turns into deadly arsenic. Because durian contains sulfur compounds, this substance can reduce the activity of acetaldehyde dehydrogenase by more than 70%, which means that alcohol cannot be completely metabolized into acetic acid, which is harmless to the human body. After drinking alcohol, it is precisely because the human body secretes acetaldehyde dehydrogenase that alcohol can be digested and then excreted from the body. However, durian inhibits the production of this enzyme. After eating durian and then drinking alcohol, people are more likely to get drunk and even cause alcohol poisoning. Of course, the doctor also said that this situation is only possible if you consume a large amount of durian. As long as you don't overdose, you don't need to worry too much. However, diabetics should also be reminded that durian and alcohol are more dangerous!