Causes of low white blood cells:
The total number of white blood cells in a normal person is 4.0~10.0×109 per liter of blood (4000~10000/mm3), and less than 4.0×109/liter (4000/mm3) is leukopenia.
Drug effects. Some drugs can lead to the body's white blood cells lower, taking these drugs, pay attention to check the white blood cells, platelets, if the white blood cells are too low is too obvious, should stop taking or change the drug. Common drugs are: a, antibiotics, mainly chloramphenicol, synthroid, they have an inhibitory effect on the hematopoietic function of the bone marrow; others, such as tetracycline, polymyxins, streptomycin occasionally; b, antitumor drugs. In the tumor cells are killed at the same time, the body's normal tissue cells are also damaged; c, antipyretic and analgesic drugs (aminopyrine, anakinra, APC, pau tazone, anti-inflammatory pain, etc. and take a larger dose, longer time related); d, antipsychotics (chlorpromazine, fenestrated, trifluoperazine); e, antithyroid drugs (propylthiouracil, tabazole, etc.); f, other: sulfonamides, quinine staring quinine, Phenytoin sodium, phenobarbital, isoniazid, mercury, antimony and so on.
Viral infections. Influenza, viral infections, viral hepatitis, etc. may lead to low white blood cells, at this time should be actively anti-viral treatment, the treatment process may be appropriate to take drugs to increase white blood cells.
3. Other diseases. Various solid tumor chemotherapy, a variety of blood diseases, immune system diseases and some chemical factors may cause low white blood cells.
Dangers of low white blood cells:
Prone to infectious diseases. White blood cells can quickly phagocytosis of foreign substances and produce antibodies, effective resistance to the invasion of pathogens, and also play an important role in the immune aspect of the disease. If the body's white blood cells are too low, it is easy to suffer from various infectious diseases, even some fatal infectious diseases.
Decreased immunity. White blood cells are responsible for the body's immunity, and a low level of white blood cells can reduce the body's immunity. A mild deficiency is called agranulocytopenia, and a severe deficiency (less than 1.5) is called agranulocytosis, which is dangerous and can lead to death from serious infections.
Symptoms of physical discomfort. Low white blood cells are usually associated with nonspecific symptoms such as dizziness, fatigue, limb weakness, loss of appetite, low-grade fever, and insomnia. A few are asymptomatic, while some patients have recurrent mouth ulcers, lung infections or urinary tract infections. Leukopenia, granulocyte deficiency, the onset of the disease is mostly acute, often with high fever, chills, headache, fatigue or extreme weakness. Sometimes necrotic ulcers can be generalized in the mucous membranes of the mouth, nasal cavity, skin, rectum, anus and vagina. These uncomfortable symptoms seriously affect the patient's work and life.