Chemicals and herbal preparations, while detoxifying, can cause metabolic burden on the liver and kidneys and produce different degrees of damage.
There are three pathways for the metabolism of alcohol in the human body: the liver, the skin and the respiratory system, of which about 95% is oxidized through the liver's enzyme system. The antidote to alcohol is to enhance the function of the liver enzyme system, play a decomposition of alcohol work principle. The principle is as follows:
Ethanol dehydrogenase - acetaldehyde dehydrogenase
Wine (ethanol) - acetaldehyde - acetic acid - carbon dioxide and water - exclusion
CH3CH2OH-C2H4O-C2H4O2
Alcohol decomposition and metabolism in the body is mainly dependent on the liver enzyme system of two kinds of enzymes: one is the enzyme of ethanol dehydrogenase, the other is the enzyme of acetaldehyde dehydrogenase. is acetaldehyde dehydrogenase.
Ethanol dehydrogenase can remove the two hydrogen atoms in the alcohol molecule, so that ethanol is broken down into acetaldehyde. Acetaldehyde dehydrogenase, on the other hand, removes two hydrogen atoms from acetaldehyde, causing it to be converted to acetic acid and eventually broken down into carbon dioxide and water.
When these two enzymes are present in the body, alcohol is broken down more quickly and the central nervous system is less likely to be affected by the effects of alcohol. The enzyme ethanol dehydrogenase is present in all human bodies and in essentially equal amounts. However, there are more people who lack the enzyme acetaldehyde dehydrogenase. This lack of acetaldehyde dehydrogenase, so that alcohol can not be completely broken down into water and carbon dioxide, but to acetaldehyde continue to stay in the body, so that people drink alcohol produced nausea and vomiting, stupor and discomfort and other symptoms of intoxication. Therefore, people who do not drink well and whose alcohol intake is below a reasonable standard are those who have an insufficient amount of acetaldehyde dehydrogenase or a complete lack of it. For people who are good drinkers, intoxication can also occur if they drink too much alcohol, too fast, exceeding the decomposition capacity of the two enzymes.
Whether a person is intoxicated depends on the concentration of ethanol in the blood. When the concentration of ethanol in the blood is 0.05-0.1%, the person starts to be hazy and get slightly drunk; and when it reaches 0.3%, the person will slur his words and stagger in his gait, which is what we often refer to as drunkenness; and if it reaches 0.7%, the person will die. The tolerance for ethanol varies greatly from person to person.